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teflubenzuron

Identification (Source:EPA,EU)

ID	1420
Name	teflubenzuron
CAS	83121-18-0
IUPAC	1-(3,5-dichloro-2,4-difluorophenyl)-3-(2,6-difluorobenzoyl)urea
Inchi	InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24)
CIPAC	450
EPA Code
Formula	C14H6Cl2F4N2O2
SMILES	Clc1cc(c(F)c(Cl)c1F)NC(=O)NC(=O)c2c(F)cccc2F
Status	Approved

Classification

Mode of Action	Systemic, chitin synthesis inhibitor
Pesticide Type	Insecticide, Veterinary treatment
Chemical Group	Benzoylurea
Classification	chitin synthesis inhibitors benzoylphenylurea chitin synthesis inhibitors

Properties (Source:PubChem)

Molecular Weight	381.11
Physical State	White to yellow crystals
AlogP	4.545
H-Bond Donor	2
H-Bond Acceptor	2
Surface Area	309.53
Polar Surface Area	58.2

Structure

Ecotoxicology (Source:PPDB,IPM)

Species	Method	Study Time	Dose Type	Value
Algae	Acute	72 hour	EC50, growth	> 0.02 mg l-1
Aquatic invertebrates	Acute	48 hour	EC50	0.0028 mg l-1
Aquatic invertebrates	Chronic	21 day	NOEC	0.000062 mg l-1
Birds	Short term dietary		LC50/LD50	> 5000 mg/kg feed
Birds	Acute		LD50	> 2250 mg kg-1
Earthworms	Acute	14 day	LD50	> 500 mg kg-1
Fish	Acute	96 hour	LC50	> 0.0065 mg l-1
Fish	Chronic	21 day	NOEC	0.0186 mg l-1
Honeybees	Acute	48 hour	LD50	72 μg bee-1
Mammals	Acute oral		LD50	> 5038 mg kg-1
Mammals	Short term dietary		NOEL	> 100 ppm diet
Mammals	Short term dietary		NOEL	> 1 mg kg-1
Sediment dwelling organisms	Chronic	28 day	NOEC, sediment	0.05 mg kg-1
	Bio-concentration factor		BCF	640
	Bio-concentration factor		CT50	0.8 days

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