triflumuron

Identification (Source:EPA,EU)

ID 1421
Name triflumuron
CAS 64628-44-0
IUPAC 1-(2-chlorobenzoyl)-3-(4-trifluoromethoxyphenyl)urea
Inchi InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)
CIPAC 548
EPA Code 118201
Formula C15H10ClF3N2O3
SMILES O=C(c1ccccc1Cl)NC(=O)Nc2ccc(OC(F)(F)F)cc2
Status Approved

Classification

Mode of Action Chitin synthesis inhibitor, Insect growth regulator
Pesticide Type Insecticide, Veterinary treatment
Chemical Group Benzoylurea
Classification benzoylphenylurea chitin synthesis inhibitors
chitin synthesis inhibitors

Properties (Source:PubChem)

Molecular Weight 358.70
Physical State Colourless crystalline powder
AlogP 5.179
H-Bond Donor 2
H-Bond Acceptor 3
Surface Area 304.49
Polar Surface Area 67.43

Structure



ChemMapper Search Option (Docunmentation of ChemMapper)

3D similarity method

2D similarity method

Compound Database



Bioactivity Database

KEGG (5,928)

PDB (7,072)


Similarity Threshold

Ecotoxicology (Source:PPDB,IPM)

Species Method Study Time Dose Type Value
Algae Acute 72 hour EC50, growth > 0.025 mg l-1
Aquatic invertebrates Acute 48 hour EC50 0.0016 mg l-1
Aquatic invertebrates Chronic 21 day NOEC 0.000032 mg l-1
Birds Short term dietary LC50/LD50 > 805 mg/kg bw/day
Birds Acute LD50 561 mg kg-1
Earthworms Acute 14 day LD50 > 500 mg kg-1
Fish Acute 96 hour LC50 > 0.021 mg l-1
Fish Chronic 21 day NOEC 0.023 mg l-1
Honeybees Acute 48 hour LD50 > 200 μg bee-1
Mammals Acute oral LD50 > 5000 mg kg-1
Mammals Short term dietary NOEL 20 ppm diet
Sediment dwelling organisms Chronic 28 day NOEC, sediment 0.00032 mg kg-1
Bio-concentration factor BCF 612
Bio-concentration factor CT50 1.36 days

Related targets

Target Name RScore (About this table)
C18 6(0,0,0,6) Details
F18 6(0,0,1,1) Details
F12 6(0,0,1,1) Details
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