sintofen
Identification (Source:EPA,EU)
ID |
1760 |
Name |
sintofen |
CAS |
130561-48-7 |
IUPAC |
1-(4-chlorophenyl)-1,4-dihydro-5-(2-methoxyethoxy)-4-oxocinnoline-3-carboxylic acid |
Inchi |
InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24) |
CIPAC |
717 |
EPA Code |
|
Formula |
C18H15ClN2O5 |
SMILES |
Clc(c([H])c([H])c1N2c3c(C(C(C(=O)O[H])=N2)=O)c(c([H])c([H])c3[H])OC([H])([H])C([H])([H])OC([H])([H])[H])c([H])c1[H] |
Status |
Approved |
Classification
Properties (Source:PubChem)
Molecular Weight |
374.8 |
Physical State |
Cream to yellow powder |
AlogP |
3.55 |
H-Bond Donor |
1 |
H-Bond Acceptor |
7 |
Surface Area |
343.23 |
Polar Surface Area |
88.43 |
Structure
Ecotoxicology (Source:PPDB,IPM)
Species |
Method |
Study Time |
Dose Type |
Value |
Algae |
Acute |
72 hour |
EC50, growth |
36.9 mg l-1 |
Aquatic invertebrates |
Chronic |
21 day |
NOEC |
7.03 mg l-1 |
Aquatic invertebrates |
Acute |
48 hour |
EC50 |
238 mg l-1 |
Aquatic plants |
Acute |
7 day |
EC50, biomass |
4.6 mg l-1 |
Birds |
Acute |
|
LD50 |
> 1439 mg kg-1 |
Birds |
Short term dietary |
|
LC50/LD50 |
> 642 mg/kg bw/day |
Earthworms |
Acute |
14 day |
LD50 |
20 mg kg-1 |
Fish |
Chronic |
21 day |
NOEC |
100 mg l-1 |
Fish |
Acute |
96 hour |
LC50 |
570 mg l-1 |
Honeybees |
Acute |
48 hour |
LD50 |
> 100 μg bee-1 |
Mammals |
Acute oral |
|
LD50 |
> 5000 mg kg-1 |
Mammals |
Short term dietary |
|
NOEL |
> 12.6 mg kg-1 |
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