fluxapyroxad

Identification (Source:EPA,EU)

ID 419
Name fluxapyroxad
CAS 907204-31-3
IUPAC
Inchi InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27)
CIPAC
EPA Code
Formula C18H12F5N3O
SMILES c1(c(cccc1)c1cc(c(c(c1)F)F)F)NC(=O)c1cn(nc1C(F)F)C
Status Approved

Classification

Mode of Action Has proventative and curative properties and works by preventing spore gemination and infection development
Pesticide Type Fungicide
Chemical Group Pyrazole
Classification anilide fungicides
pyrazole fungicides

Properties (Source:PubChem)

Molecular Weight 381.31
Physical State Crystalline powder
AlogP 4.281
H-Bond Donor 1
H-Bond Acceptor 2
Surface Area 326.62
Polar Surface Area 46.92

Structure



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3D similarity method

2D similarity method

Compound Database



Bioactivity Database

KEGG (5,928)

PDB (7,072)


Similarity Threshold

Ecotoxicology (Source:PPDB,IPM)

Species Method Study Time Dose Type Value
Algae Acute 72 hour EC50, growth 0.70 mg l-1
Aquatic invertebrates Chronic 21 day NOEC 0.5 mg l-1
Aquatic invertebrates Acute 48 hour EC50 6.78 mg l-1
Aquatic plants Acute 7 day EC50, biomass 3.43 mg l-1
Birds Short term dietary LC50/LD50 > 912 mg/kg/day
Birds Acute LD50 > 2000 mg kg-1
Earthworms Acute 14 day LD50 > 1000 mg kg-1
Fish Acute 96 hour LC50 0.546 mg l-1
Fish Chronic 21 day NOEC 0.036 mg l-1
Honeybees Acute 48 hour LD50 > 100 μg bee-1
Mammals Acute oral LD50 > 2000 mg kg-1
Bio-concentration factor BCF 36
Bio-concentration factor CT50 0.73 days
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