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cyproconazole

Identification (Source:EPA,EU)

ID	527
Name	cyproconazole
CAS	94361-06-5
IUPAC
Inchi	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3
CIPAC	600
EPA Code	128993
Formula	C15H18ClN3O
SMILES	Clc1ccc(cc1)C(O)(C(C)C2CC2)Cn3ncnc3
Status	Approved

Classification

Mode of Action	Systemic with protective, curative and eradicant action. Disrupts membrane function. An ergosterol-biosynthesis inhibitor.
Pesticide Type	Fungicide
Chemical Group	Triazole
Classification	conazole fungicides (triazoles)

Properties (Source:PubChem)

Molecular Weight	291.78
Physical State	Fine white powder
AlogP	2.917
H-Bond Donor	1
H-Bond Acceptor	3
Surface Area	277.54
Polar Surface Area	50.94

Structure

Ecotoxicology (Source:PPDB,IPM)

Species	Method	Study Time	Dose Type	Value
Algae	Acute	72 hour	EC50, growth	0.099 mg l-1
Algae	Chronic	96 hour	NOEC, growth	0.02 mg l-1
Aquatic crustaceans	Acute	96 hour	LC50	8.3 mg l-1
Aquatic invertebrates	Chronic	21 day	NOEC	0.29 mg l-1
Aquatic invertebrates	Acute	48 hour	EC50	> 22 mg l-1
Aquatic plants	Acute	7 day	EC50, biomass	0.059 mg l-1
Birds	Short term dietary		LC50/LD50	> 146 mg/kg
Birds	Acute		LD50	94 mg kg-1
Earthworms	Chronic	14 day	NOEC, reproduction	0.75 mg kg-1
Earthworms	Acute	14 day	LD50	168 mg kg-1
Fish	Chronic	21 day	NOEC	0.65 mg l-1
Fish	Acute	96 hour	LC50	19.0 mg l-1
Honeybees	Acute	48 hour	LD50	> 100 μg bee-1
Mammals	Acute oral		LD50	< 350 mg kg-1
Mammals	Short term dietary		NOEL	1.84 mg kg-1
Mammals	Short term dietary		NOEL	15 ppm diet
Sediment dwelling organisms	Chronic	28 day	NOEC, sediment	50.0 mg kg-1
	Bio-concentration factor		BCF	28
	Bio-concentration factor		CT50	1 days

Related targets

Target Name	RScore (About this table)
constitutive androstane receptor	7(0,0,1,2)	Details
C18	3(0,0,0,3)	Details
catalase	2(0,0,0,2)	Details

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