oxadiazon

Identification (Source:EPA,EU)

ID 995
Name oxadiazon
CAS 19666-30-9
IUPAC
Inchi InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3
CIPAC 213
EPA Code 109001
Formula C15H18Cl2N2O3
SMILES CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl
Status Approved

Classification

Mode of Action Selective with contact action. Inhibits protoporphyrinogen oxidase, leading to irreversible cell membrane damage.
Pesticide Type Herbicide
Chemical Group Oxidiazole
Classification oxadiazolone herbicides

Properties (Source:PubChem)

Molecular Weight 345.2
Physical State Colourless crystals
AlogP 5.224
H-Bond Donor 0
H-Bond Acceptor 4
Surface Area 332.53
Polar Surface Area 51.13

Structure



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3D similarity method

2D similarity method

Compound Database



Bioactivity Database

KEGG (5,928)

PDB (7,072)


Similarity Threshold

Ecotoxicology (Source:PPDB,IPM)

Species Method Study Time Dose Type Value
Algae Acute 72 hour EC50, growth 0.004 mg l-1
Aquatic crustaceans Acute 96 hour LC50 0.23 mg l-1
Aquatic invertebrates Chronic 21 day NOEC 0.03 mg l-1
Aquatic invertebrates Acute 48 hour EC50 > 2.4 mg l-1
Aquatic plants Acute 7 day EC50, biomass 0.057 mg l-1
Birds Acute LD50 > 2150 mg kg-1
Birds Short term dietary LC50/LD50 > 5000 mg/Kg diet
Earthworms Acute 14 day LD50 > 500 mg kg-1
Earthworms Chronic 14 day NOEC, reproduction 10.0 mg kg-1
Fish Acute 96 hour LC50 1.2 mg l-1
Fish Chronic 21 day NOEC 0.00088 mg l-1
Honeybees Acute 48 hour LD50 > 100 μg bee-1
Mammals Acute oral LD50 > 5000 mg kg-1
Mammals Short term dietary NOEL 10 ppm diet
Bio-concentration factor CT50 2.5 days
Bio-concentration factor BCF 243

Related targets

Target Name RScore (About this table)
protoporphyrinogen oxidase 238(2,4,4,18) Details
transferase 13(0,0,2,3) Details
palmitoyl CoA oxidase 7(0,0,1,2) Details
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