| Name | calmodulin |
|---|---|
| Synonyms | CALM; CAM; CALM 1; CALM 2; CALM 3; CALM1; CALM2; CALM3… |
| Name | lindane |
|---|---|
| CAS | (1α,2α,3β,4α,5α,6β)-1,2,3,4,5,6-hexachlorocyclohexane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 7531829 | Tusell JM, Barron S, Serratosa J: Anticonvulsant activity of calmodulin antagonist W-7 in convulsions induced by lindane and BayK-8644: effects in c-fos expression. Neurotoxicology. 1994 Fall;15(3):751-6. Our results suggest that lindane as BayK-8644 may activate voltage-dependent channels leading to calmodulin activation. |
143(1,3,3,3) | Details |
| 7694769 | Tusell JM, Barron S, Serratosa J: Anticonvulsant activity of delta-HCH, calcium channel blockers and calmodulin antagonists in seizures induced by lindane and other convulsant drugs. Brain Res. 1993 Sep 17;622(1-2):99-104. |
62(0,2,2,2) | Details |
| 1382176 | Vendrell M, Pujol MJ, Tusell JM, Serratosa J: Effect of different convulsants on calmodulin levels and proto-oncogene c-fos expression in the central nervous system. Brain Res Mol Brain Res. 1992 Aug;14(4):285-92. In the present study, a relationship between convulsant activity and two cellular events, changes in calmodulin (CaM) concentration and proto-oncogene c-fos expression has been considered. c-fos has been found activated after the administration of the organochlorine insecticide lindane, the Ca2+ channel agonist Bay K, and |
32(0,1,1,2) | Details |
| 7543649 | Barron S, Tusell JM, Serratosa J: Effect of hexachlorocyclohexane isomers on calmodulin mRNA expression in the central nervous system. Brain Res Mol Brain Res. 1995 Jun;30(2):279-86. We have investigated the possibility of differential expression of two calmodulin genes, CaM I and CaM II, which are expressed strongly in neuronal cells in the adult rat brain, after treatment with the gamma (lindane) and the delta isomers of the hexachlorocyclohexane (HCH). |
15(0,0,2,5) | Details |
| 9674959 | Kang JJ, Chen IL, Yen-Yang HF: Mediation of gamma-hexachlorocyclohexane-induced DNA fragmentation in HL-60 cells through intracellular Ca2+ release pathway. Food Chem Toxicol. 1998 Jun;36(6):513-20. The DNA fragmentation induced was inhibited by intracellular Ca2+ chelator, calmodulin antagonist and Ca2+ sensitive endonuclease inhibitor. |
2(0,0,0,2) | Details |
| 7680676 | Meera P, Tripathi O, Kamboj KK, Rao PR: Role of in biphasic immunomodulation by gamma-HCH (lindane) in mice. Immunopharmacol Immunotoxicol. 1993 Jan;15(1):113-29. Lymphocyte proliferation was inhibited during both the phases of immune response by a calcium channel blocker, and by trifluoperazine, a calmodulin inhibitor. |
1(0,0,0,1) | Details |
| 7512927 | Cristofol RM, Rodriguez-Farre E: Hippocampal release is modulated by gamma- and delta-hexachlorocyclohexane isomers: which mechanisms are involved?. Eur J Pharmacol. 1994 Feb 11;252(3):305-12. Likewise, under activation of protein kinase C by phorbol 12,13-dibutyrate (PDB) or inhibition of calmodulin by N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7), the stimulatory effect of gamma-hexachlorocyclohexane remained almost unchanged. |
1(0,0,0,1) | Details |