Protein Information

Name C23
Synonyms C23; NCL; Nucleolin; Protein C23; Nucleolins; Protein C23s

Compound Information

Name brassinolide
CAS

Reference List

PubMed Abstract RScore(About this table)
8612270 Szekeres M, Nemeth K, Koncz-Kalman Z, Mathur J, Kauschmann A, Altmann T, Redei GP, Nagy F, Schell J, Koncz C: Brassinosteroids rescue the deficiency of CYP90, a cytochrome P450, controlling cell elongation and de-etiolation in Arabidopsis. Cell. 1996 Apr 19;85(2):171-82.

The phenotype of the cpd mutant is restored to wild type both by feeding with C23-hydroxylated brassinolide precursors and by ectopic overexpression of the CPD cDNA.
81(1,1,1,1) Details
19537178 Khripach VA, Zhabinskii VN, Parkhimovich KV, Gyliakevich OV: [Synthesis of brassinolide and its biosynthetic precursors using methyl-3-hydroxy-2-methylpropionate]. Bioorg Khim. 2009 Mar-Apr;35(2):260-9.

Stereochemistry of a methyl group at the C24 atom was provided by the choice of the desired enanthiomer of methyl-3-hydroxy-2-methylpropionate and by the sequence of its conversions into the chiral intermediate that was necessary for the formation of the C23-C28 fragment of the side chain.
1(0,0,0,1) Details