Protein Information

Name CYP2E1
Synonyms CPE 1; Flavoprotein linked monooxygenase; Xenobiotic monooxygenase; Microsomal monooxygenase; CPE1; CYP2E; CYP2E1; CYP2E1 protein…

Compound Information

Name bromadiolone
CAS

Reference List

PubMed Abstract RScore(About this table)
18080289 Markussen MD, Heiberg AC, Fredholm M, Kristensen M: Differential expression of cytochrome P450 genes between bromadiolone-resistant and anticoagulant-susceptible Norway rats: a possible role for pharmacokinetics in bromadiolone resistance. Pest Manag Sci. 2008 Mar;64(3):239-48.

CONCLUSION: Results suggest that bromadiolone resistance in a Danish strain of Norway rats involves enhanced anticoagulant metabolism catalysed by cytochrome P450-2e1, -3a2 and -3a3.
119(1,2,3,4) Details