Protein Information

Name prothrombin
Synonyms Coagulation factor II; Coagulation factor II variant; F2; F2 protein; F2 protein precursor; Factor II; PT; Prothrombin…

Compound Information

Name pindone
CAS

Reference List

PubMed Abstract RScore(About this table)
1929992 Martin GR, Sutherland RJ, Robertson ID, Kirkpatrick WE, King DR, Hood PJ: Assessment of the potential toxicity of a poison for rabbits, pindone (2-pivalyl 1, 3 indandione), to domestic animals. Aust Vet J. 1991 Jul;68(7):241-3.

The toxicity of pindone, a rabbit poison, to horses, cattle, goats, chickens, dogs and cats was investigated, using extension of prothrombin time (PT) as an index of poisoning.
6(0,0,1,1) Details
15694595 Robinson MH, Twigg LE, Wheeler SH, Martin GR: Effect of the anticoagulant, pindone, on the breeding performance and survival of merino sheep, Ovis aries. Comp Biochem Physiol B Biochem Mol Biol. 2005 Mar;140(3):465-73.

Prothrombin times (PT) increased up to 4-fold in treated sheep, and haemorrhage occurred in some instances, particularly with the double dose treatment.
1(0,0,0,1) Details