Protein Information

Name IgE
Synonyms IGHE; Ig epsilon chain C region; IgE; immunoglobulin heavy constant epsilon; Ig epsilon chain C regions; IgEs; immunoglobulin heavy constant epsilons

Compound Information

Name valone
CAS

Reference List

PubMed Abstract RScore(About this table)
2538500 Shalit M, Valone FH, Atkins PC, Ratnoff WD, Goetzl EJ, Zweiman B: Late appearance of phospholipid platelet-activating factor and leukotriene B4 in human skin after repeated antigen challenge. J Allergy Clin Immunol. 1989 Mar;83(3):691-6.


Continuous antigen exposure thus results in the persistent release of histamine and LTB4 and the late appearance of PAF, all of which may contribute to the chronicity of allergic disorders and may have a bearing on the IgE-mediated, late-phase cutaneous response.
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3021806 Payan DG, Wong MY, Chernov-Rogan T, Valone FH, Pickett WC, Blake VA, Gold WM, Goetzl EJ: Alterations in human leukocyte function induced by ingestion of eicosapentaenoic acid. J Clin Immunol. 1986 Sep;6(5):402-10.


Only the high dose led to inhibition of PMN leukocyte chemotaxis to multiple stimuli by a mean of 57-70% (P less than 0.01), without altering monocyte chemotaxis, the production of platelet-activating factor by mononuclear leukocytes, or the IgE-dependent release of histamine from basophils.
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