Protein Information

Name C3b
Synonyms ASP; Acylation stimulating protein; C3; C3a; C3b; CPAMD 1; CPAMD1; Complement C3…

Compound Information

Name valone
CAS

Reference List

PubMed Abstract RScore(About this table)
6848449 Valone FH, Goetzl EJ: Specific binding by human polymorphonuclear leucocytes of the immunological mediator 1-O-hexadecyl/octadecyl-2-acetyl-sn-glycero-3-phosphorylcholine. Immunology. 1983 Jan;48(1):141-9.


Similar structural requirements were observed for the elicitation of PMN leucocyte chemotaxis and the enhancement of the expression of PMN leucocyte C3b receptors by AGEPC.
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6088172 Valone FH: Regulation of human leukocyte function by lipoxygenase products of arachidonic acid. Contemp Top Immunobiol. 1984;14:155-70.


Nanomolar concentrations of LTB4 elicit PMN chemotaxis both in vitro and in vivo, and 3- to 10-fold higher concentrations of LTB4 promote lysosomal degranulation, PMN leukocyte aggregation, and adherence, in addition to enhancing the expression of neutrophil and eosinophil C3b receptors.
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