Protein Information

Name interferon gamma
Synonyms IFG; IFI; IFN gamma; IFNG; IFNgamma; Immune interferon; Interferon gamma; Interferon gamma precursor…

Compound Information

Name valone
CAS

Reference List

PubMed Abstract RScore(About this table)
2117030 Barthelson R, Valone F: Interaction of platelet-activating factor with interferon-gamma in the stimulation of interleukin-1 production by human monocytes. J Allergy Clin Immunol. 1990 Aug;86(2):193-201.

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3169845 Valone FH, Philip R, Debs RJ: Enhanced human monocyte cytotoxicity by platelet-activating factor. Immunology. 1988 Aug;64(4):715-8.


Maximal PAF-induced cytotoxicity was 68 +/- 6%, which was similar to that induced by optimal concentrations of tumour necrosis factor (TNF) and interferon-gamma.
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17698695 Bar-Or A, Vollmer T, Antel J, Arnold DL, Bodner CA, Campagnolo D, Gianettoni J, Jalili F, Kachuck N, Lapierre Y, Niino M, Oger J, Price M, Rhodes S, Robinson WH, Shi FD, Utz PJ, Valone F, Weiner L, Steinman L, Garren H: Induction of antigen-specific tolerance in multiple sclerosis after immunization with DNA encoding myelin basic protein in a randomized, placebo-controlled phase 1/2 trial. Arch Neurol. 2007 Oct;64(10):1407-15. Epub 2007 Aug 13.


These immune changes consisted of a marked decrease in proliferation of interferon-gamma-producing, myelin-reactive CD4+ T cells from peripheral blood and a reduction in titers of myelin-specific autoantibodies from cerebral spinal fluid as assessed by protein microarrays.
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