Protein Information

Name 3 mercaptopyruvate sulfurtransferase
Synonyms 3 mercaptopyruvate sulfurtransferase; MST; 3 mercaptopyruvate sulfurtransferase variant; MPST; MPST protein; Mercaptopyruvate sulfurtransferase; TST 2; TST2…

Compound Information

Name sulfur
CAS sulfur

Reference List

PubMed Abstract RScore(About this table)
19762467 Westrop GD, Georg I, Coombs GH: The mercaptopyruvate sulfurtransferase of Trichomonas vaginalis links cysteine catabolism to the production of thioredoxin persulfide. J Biol Chem. 2009 Nov 27;284(48):33485-94. Epub 2009 Sep 17.

This consists of an aspartate aminotransferase (TvAspAT1), which transaminates cysteine to form 3-mercaptopyruvate (3-MP), and mercaptopyruvate sulfurtransferase (TvMST), which transfers the sulfur of 3-MP to a nucleophilic acceptor, generating pyruvate.
32(0,1,1,2) Details
20191298 Kimura H: Hydrogen sulfide: its production, release and functions. . Amino Acids. 2010 Feb 27.

It is produced by three enzymes, cystathionine beta-synthase, cystathionine gamma-lyase and 3-mercaptopyruvate sulfurtransferase along with cysteine aminotransferase.
In addition to an immediate release of H (2) S from producing enzymes, it can be stored as bound sulfane sulfur, which may release H (2) S in response to physiological stimuli.
1(0,0,0,1) Details