Protein Information

Name tumor necrosis factor
Synonyms Cachectin; DIF; TNF; TNF alpha; TNF a; TNFA; TNFSF 2; TNFSF2…

Compound Information

Name valone
CAS

Reference List

PubMed Abstract RScore(About this table)
1668105 Ruis NM, Rose JK, Valone FH: Tumor necrosis factor release by human monocytes stimulated with platelet-activating factor. Lipids. 1991 Dec;26(12):1060-4.

2(0,0,0,2) Details
3053456 Valone SE, Rich EA, Wallis RS, Ellner JJ: Expression of tumor necrosis factor in vitro by human mononuclear phagocytes stimulated with whole Mycobacterium bovis BCG and mycobacterial antigens. Infect Immun. 1988 Dec;56(12):3313-5.

2(0,0,0,2) Details
8045673 Shames R, Ruis NM, Valone FH: Tumor necrosis factor release by murine macrophages stimulated by the cytotoxic ether lipid 1-O-hexadecyl-2-O-methyl-SN-glycero-3-phosphorylcholine (ET-18-O-OCH3). Int J Immunopharmacol. 1994 Apr;16(4):335-43.

1(0,0,0,1) Details
3141509 Valone FH, Epstein LB: Biphasic platelet-activating factor synthesis by human monocytes stimulated with IL-1-beta, tumor necrosis factor, or IFN-gamma. J Immunol. 1988 Dec 1;141(11):3945-50.

1(0,0,0,1) Details
7545221 Valone FH, Kaufman PA, Guyre PM, Lewis LD, Memoli V, Deo Y, Graziano R, Fisher JL, Meyer L, Mrozek-Orlowski M, et al.: Phase Ia/Ib trial of bispecific antibody MDX-210 in patients with advanced breast or ovarian cancer that overexpresses the proto-oncogene HER-2/neu. J Clin Oncol. 1995 Sep;13(9):2281-92.


Elevated plasma levels of the monocyte products tumor necrosis factor alpha (TNF alpha), interleukin-6 (IL-6), granulocyte colony-stimulating factor (G-CSF), and neopterin were observed with maximal levels at doses > or = 7.0 mg/m2.
1(0,0,0,1) Details