Protein Information

Name ISD11
Synonyms CGI 203; ISD11; LYR motif containing 4; LYR motif containing protein 4; LYRM 4; LYRM4; LYR motif containing 4s; LYR motif containing protein 4s

Compound Information

Name sulfur
CAS sulfur

Reference List

PubMed Abstract RScore(About this table)
19454487 Shi Y, Ghosh MC, Tong WH, Rouault TA: Human ISD11 is essential for both iron-sulfur cluster assembly and maintenance of normal cellular iron homeostasis. Hum Mol Genet. 2009 Aug 15;18(16):3014-25. Epub 2009 May 18.

Here, we have cloned and characterized human ISD11 and shown that human ISD11 forms a stable complex in vivo with the human cysteine desulfurase (ISCS), which generates the inorganic sulfur needed for Fe-S protein biogenesis.
41(0,1,2,6) Details