Protein Information

Name thrombin
Synonyms Coagulation factor II; Coagulation factor II variant; F2; F2 protein; F2 protein precursor; Factor II; PT; Prothrombin…

Compound Information

Name valone
CAS

Reference List

PubMed Abstract RScore(About this table)
3322269 Valone FH, Johnson B: Modulation of platelet-activating-factor-induced calcium influx and intracellular calcium release in platelets by phorbol esters. Biochem J. 1987 Nov 1;247(3):669-74.


The mechanisms by which platelet-activating factor (PAF) and thrombin increase intracellular calcium were examined.
2(0,0,0,2) Details
3255740 Valone FH, Stricker RB, Zamora PO, Shah VO, Mann PL: Technetium-99m labeled 50H.19 antibody fragments: interaction of the antibody with platelets. Int J Rad Appl Instrum B. 1988;15(4):439-50.


The intact antibody potentiated platelet aggregation induced by platelet-activating factor or thrombin.
1(0,0,0,1) Details
2578151 Valone FH, Johnson B: Modulation of cytoplasmic calcium in human platelets by the phospholipid platelet-activating factor 1-O-alkyl-2-acetyl-SN-glycero-3-phosphorylcholine. J Immunol. 1985 Feb;134(2):1120-4.


Pretreatment of platelets with AGEPC rendered the platelets specifically unresponsive to repeat stimulation with AGEPC in terms of both platelet aggregation and increased [Ca2+] i, whereas the platelet response to thrombin was undiminished by pretreatment with AGEPC.
1(0,0,0,1) Details