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Camaschella C: Hereditary sideroblastic anemias: pathophysiology, diagnosis, and treatment. Semin Hematol. 2009 Oct;46(4):371-7.
The identification of other genes, such as adenosine triphosphate (ATP) binding cassette B7 (ABCB7) and glutaredoxin 5 (GLRX5), has strengthened the role of iron sulfur cluster biogenesis in sideroblast formation and revealed a complex interplay between pathways of mitochondrial iron utilization and cytosolic iron sensing by the iron-regulatory proteins (IRPs). |
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