Protein Information

Name cytochrome b
Synonyms COB; CYTB; Cytochrome b; Cytochrome b of complex III; MT CYB; MTCYB; mitochondrially encoded cytochrome b; Cytochrome bs…

Compound Information

Name sulfur
CAS sulfur

Reference List

PubMed Abstract RScore(About this table)
19674969 Tsunoyama Y, Bernat G, Dyczmons NG, Schneider D, Rogner M: Multiple Rieske proteins enable short- and long-term light adaptation of Synechocystis sp. J Biol Chem. 2009 Oct 9;284(41):27875-83. Epub 2009 Aug 12.


In contrast to eukaryotes, most cyanobacteria contain several isoforms of the Rieske iron-sulfur protein, PetC, resulting in heterogeneity in the composition of the cytochrome b (6) f complexes.
3(0,0,0,3) Details
19577535 Schultze M, Forberich B, Rexroth S, Dyczmons NG, Roegner M, Appel J: Localization of cytochrome b6f complexes implies an incomplete respiratory chain in cytoplasmic membranes of the cyanobacterium Synechocystis sp. Biochim Biophys Acta. 2009 Dec;1787(12):1479-85. Epub 2009 Jul 3.


The cytochrome b (6) f complex is an integral part of the photosynthetic and respiratory electron transfer chain of oxygenic photosynthetic bacteria.
3(0,0,0,3) Details
20025846 Berry EA, Huang LS, Lee DW, Daldal F, Nagai K, Minagawa N: Ascochlorin is a novel, specific inhibitor of the mitochondrial cytochrome bc1 complex. Biochim Biophys Acta. 2010 Mar;1797(3):360-70. Epub 2009 Dec 16.


On the other hand, it suppressed the reduction of cytochrome b and the generation of superoxide anion in the presence of antimycin A (3) in a fashion similar to the Q (o) site inhibitor myxothiazol.
3(0,0,0,3) Details
19861232 Sang M, Ma F, Xie J, Chen XB, Wang KB, Qin XC, Wang WD, Zhao JQ, Li LB, Zhang JP, Kuang TY: High-light induced singlet oxygen formation in cytochrome b (6) f complex from Bryopsis corticulans as detected by EPR spectroscopy. Biophys Chem. 2010 Jan;146(1):7-12. Epub 2009 Oct 6.

2(0,0,0,2) Details
19478336 Rottenberg H, Covian R, Trumpower BL: Membrane potential greatly enhances superoxide generation by the cytochrome bc1 complex reconstituted into phospholipid vesicles. J Biol Chem. 2009 Jul 17;284(29):19203-10. Epub 2009 May 28.


The rate of superoxide generation by the reconstituted bc (1) complex increased exponentially with increased magnitude of the membrane potential, a finding that is compatible with the suggestion that membrane potential inhibits electron transfer from the cytochrome b (L) to b (H) hemes, thereby promoting the formation of a ubisemiquinone radical that interacts with oxygen to generate superoxide.
1(0,0,0,1) Details
19774111 Chen QL, Tang XS, Yao WJ, Lu SQ: Bioinformatics analysis of the complete sequences of cytochrome b of Takydromus sylvaticus and modeling the tertiary structure of encoded protein. Int J Biol Sci. 2009 Sep 22;5(6):596-602.

Thermostability analysis shows that the CD-loop region is unstable thermodynamically and may provide mobility to amino acids located at the heme, and might provide high flexibility to the top of ISP (iron-sulfur protein) and the cavity region of Qo binding site.
2(0,0,0,2) Details
19660431 Hughes LM, Covian R, Gribble GW, Trumpower BL: Probing binding determinants in center P of the cytochrome bc (1) complex using novel hydroxy-naphthoquinones. Biochim Biophys Acta. 2010 Jan;1797(1):38-43. Epub 2009 Aug 4.


It acts by inhibiting the cytochrome bc (1) complex via interactions with the Rieske iron-sulfur protein and cytochrome b in the ubiquinol oxidation pocket.
1(0,0,0,1) Details
20091229 Baymann F, Nitschke W: Heliobacterial Rieske/cytb complex. . Photosynth Res. 2010 Jan 21.


It is composed of a diheme cytochrome c, and a Rieske iron-sulfur protein, together with transmembrane cytochrome b (6) and subunit IV.
1(0,0,0,1) Details
19549324 Willett CS, Ladner JT: Investigations of fine-scale phylogeography in Tigriopus californicus reveal historical patterns of population divergence. BMC Evol Biol. 2009 Jun 23;9:139.


RESULTS: Sequence variation in both cytochrome b (CYTB, mtDNA) and the rieske iron-sulfur protein (RISP, nuclear) are examined at a fine scale within four different regions for populations of T. californicus.
1(0,0,0,1) Details
20075289 Tinsley N, Iqbal M, Pumford NR, Lassiter K, Ojano-Dirain C, Wing T, Bottje W: Investigation of mitochondrial protein expression and oxidation in heart muscle in low and high feed efficient male broilers in a single genetic line. Poult Sci. 2010 Feb;89(2):349-52.


The expression of 6 electron transport chain proteins [complex II, 70S subunit (CII 70S); iron-sulfur-containing protein (ISP), cytochrome b (Cyt b), cytochrome (Cyt c1) (of complex III); and cytochrome oxidase subunit II (COX II) (of complex IV)] and adenine nucleotide translocator 1 (ANT1) were higher in low feed efficiency heart mitochondria, but 1 protein [NAD subunit 6c (NAD6c) (complex I)] was higher in high feed efficiency birds.
1(0,0,0,1) Details