Name | aconitases |
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Synonyms | ACO 1; ACO1; Aconitase; Aconitase 1; Aconitase 1 variant; Aconitate hydratase; Citrate hydro lyase; Ferritin repressor protein… |
Name | sulfur |
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CAS | sulfur |
PubMed | Abstract | RScore(About this table) | |
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20053667 | Condo I, Malisan F, Guccini I, Serio D, Rufini A, Testi R: Molecular control of the cytosolic aconitase/IRP1 switch by extramitochondrial frataxin. Hum Mol Genet. 2010 Apr 1;19(7):1221-9. Epub 2010 Jan 6. We demonstrate that the extramitochondrial form of frataxin directly interacts with cytosolic aconitase/iron regulatory protein-1 (IRP1), a bifunctional protein alternating between an enzymatic and a RNA-binding function through the 'iron-sulfur switch' mechanism. |
34(0,1,1,4) | Details |
19454487 | Shi Y, Ghosh MC, Tong WH, Rouault TA: Human ISD11 is essential for both iron-sulfur cluster assembly and maintenance of normal cellular iron homeostasis. Hum Mol Genet. 2009 Aug 15;18(16):3014-25. Epub 2009 May 18. Using RNA-interference techniques, we have shown that suppression of human ISD11 inactivated mitochondrial and cytosolic aconitases. |
2(0,0,0,2) | Details |