Protein Information

Name electron transferring flavoprotein dehydrogenase
Synonyms ETF dehydrogenase; MADD; ETF QO; ETF ubiquinone oxidoreductase; ETFDH; ETFQO; Electron transfer flavoprotein; Electron transfer flavoprotein dehydrogenase…

Compound Information

Name sulfur
CAS sulfur

Reference List

PubMed Abstract RScore(About this table)
19774399 Chew DS, Mah AK, Baillie DL: Characterizing the transcriptional regulation of let-721, a Caenorhabditis elegans homolog of human electron flavoprotein dehydrogenase. Mol Genet Genomics. 2009 Dec;282(6):555-70. Epub 2009 Sep 23.


LET-721 is the Caenorhabditis elegans ortholog of electron-transferring flavoprotein dehydrogenase (ETFDH).
5(0,0,0,5) Details
19758981 Wen B, Dai T, Li W, Zhao Y, Liu S, Zhang C, Li H, Wu J, Li D, Yan C: Riboflavin-responsive lipid-storage myopathy caused by ETFDH gene mutations. J Neurol Neurosurg Psychiatry. 2010 Feb;81(2):231-6. Epub 2009 Sep 15.

4(0,0,0,4) Details
20020044 Song Y, Selak MA, Watson CT, Coutts C, Scherer PC, Panzer JA, Gibbs S, Scott MO, Willer G, Gregg RG, Ali DW, Bennett MJ, Balice-Gordon RJ: Mechanisms underlying metabolic and neural defects in zebrafish and human multiple acyl-CoA dehydrogenase deficiency (MADD). PLoS One. 2009 Dec 17;4(12):e8329.

3(0,0,0,3) Details
20032466 Seifert EL, Estey C, Xuan JY, Harper ME: Electron transport chain-dependent and -independent mechanisms of mitochondrial H2O2 emission during long-chain fatty acid oxidation. J Biol Chem. 2010 Feb 19;285(8):5748-58. Epub 2009 Dec 23.


Determinations of topology and membrane potential as well as use of inhibitors revealed complex III and the electron transfer flavoprotein (ETF) and ETF-oxidoreductase, as likely sites of ROS production.
1(0,0,0,1) Details