Protein Information

Name mitogen activated protein kinase (protein family or complex)
Synonyms MAPK; mitogen activated protein kinase; mitogen activated protein kinases

Compound Information

Name dieldrin
CAS

Reference List

PubMed Abstract RScore(About this table)
15888667 Ledirac N, Antherieu S, d'Uby AD, Caron JC, Rahmani R: Effects of organochlorine insecticides on MAP kinase pathways in human HaCaT keratinocytes: key role of reactive oxygen species. Toxicol Sci. 2005 Aug;86(2):444-52. Epub 2005 May 11.

The aim of this study was to investigate the effects of four OCs (dieldrin, endosulfan, heptachlor, and lindane) on mitogen-activated protein kinase (MAPK) cascades and more specifically to identify the mechanism underlying OC-induced ERK1/2 activation.
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15770161 Kim DK, Kim JS, Kim JE, Kim SJ, Lee JS, Kim DJ, Son JH, Chun HS: Heme oxygenase-1 induction by dieldrin in dopaminergic cells. Neuroreport. 2005 Apr 4;16(5):509-12.

Furthermore, both the p38 and JNK mitogen-activated protein kinase pathways are utilized for HO-1 transcriptional activation by dieldrin.
31(0,1,1,1) Details