Protein Information

Name protein kinase C delta
Synonyms MAY1; May1; PRKCD; Protein kinase C delta; Protein kinase C delta type; nPKC delta; May1s; Protein kinase C deltas…

Compound Information

Name dieldrin
CAS

Reference List

PubMed Abstract RScore(About this table)
18945348 Kanthasamy AG, Kitazawa M, Yang Y, Anantharam V, Kanthasamy A: Environmental neurotoxin dieldrin induces apoptosis via caspase-3-dependent proteolytic activation of protein kinase C delta (PKCdelta): Implications for neurodegeneration in Parkinson's disease. Mol Brain. 2008 Oct 22;1(1):12.
 162(2,2,2,2) Details
20097775 Song C, Kanthasamy A, Anantharam V, Sun F, Kanthasamy AG: Environmental neurotoxic pesticide increases histone acetylation to promote apoptosis in dopaminergic neuronal cells: relevance to epigenetic mechanisms of neurodegeneration. Mol Pharmacol. 2010 Apr;77(4):621-32. Epub 2010 Jan 22.

The novel HAT inhibitor anacardic acid significantly attenuated dieldrin-induced histone acetylation, Protein kinase C delta proteolytic activation and DNA fragmentation in dopaminergic cells protected against dopaminergic neuronal degeneration in primary mesencephalic neuronal cultures.		 81(1,1,1,1) Details