Protein Information

Name NF kappa B
Synonyms DNA binding factor KBF1; EBP 1; KBF 1; KBF1; NF kappa B; NFKB p105; NFKB p50; NFKB 1…

Compound Information

Name dieldrin
CAS

Reference List

PubMed Abstract RScore(About this table)
17963131 Ansari RA, Gandy J: Determining the transrepression activity of xenoestrogen on nuclear factor-kappa B in Cos-1 cells by estrogen receptor-alpha. Int J Toxicol. 2007 Sep-Oct;26(5):441-9.

The ability of selected xenoestrogens (methoxychlor [MXC], dieldrin, and o',p'-DDT) to transrepress the NF-kappa B-mediated transcription in Cos-1 cells was evaluated by cotransfection of human estrogen receptor-alpha (hERalpha).
35(0,1,1,5) Details
18958706 Pruett SB, Fan R, Oppenheimer S: Greater than additive suppression of TLR3-induced IL-6 responses by administration of dieldrin and atrazine. J Immunotoxicol. 2006 Dec 1;3(4):253-62.

The suppression of IL-6 production and inhibition of NF-kappa B activation was greater than additive when comparing animals given both compounds to those given either compound separately.
1(0,0,0,1) Details