| Name | adenylate cyclase |
|---|---|
| Synonyms | AH related protein; HCA2; ATP pyrophosphate lyase; Adenylate cyclase; Adenylyl cyclase soluble; HCA 2; RP1 313L4.2; SAC… |
| Name | dieldrin |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 7690584 | Carrero I, Rodriguez-Henche N, Guijarro LG, Recio MN, Perez-Albarsanz MA, Prieto JC: Lindane decreases forskolin-stimulated cyclic AMP accumulation but does not modify Gs in rat enterocytes. Cell Signal. 1993 Jul;5(4):453-62. There was a certain degree of specificity since delta-HCCH was indeed more potent, whereas dieldrin and endrin (non-lindane related halogenated compounds) behaved as lindane, and alpha- and beta-HCCH were poorly efficient on the inhibition of forskolin stimulation of adenylate cyclase activity. |
83(1,1,1,3) | Details |
| 2616064 | Kodavanti PR, Mehrotra BD, Chetty SC, Desaiah D: Inhibition of calmodulin activated adenylate cyclase in rat brain by selected insecticides. Neurotoxicology. 1989 Summer;10(2):219-28. Although dieldrin and aldrin inhibited basal adenylate cyclase in a concentration dependent manner, they did not exhibit a similar pattern on CaM activated adenylate cyclase. |
7(0,0,0,7) | Details |
| 2845111 | Kodavanti PR, Mehrotra BD, Chetty SC, Desaiah D: Effect of selected insecticides on rat brain synaptosomal adenylate cyclase and phosphodiesterase. J Toxicol Environ Health. 1988;25(2):207-15. The present studies were initiated to study the effect of plictran, chlordecone, toxaphene, aldrin, dieldrin, endrin, isodrin, and telodrin on enzymes involved in cyclic AMP metabolism. |
5(0,0,0,5) | Details |
| 2467674 | Carrero I, Fernandez-Moreno MD, Perez-Albarsanz MA, Prieto JC: Lindane effect upon the vasoactive intestinal peptide receptor/effector system in rat enterocytes. Biochem Biophys Res Commun. 1989 Mar 31;159(3):1391-6. Lindane action exhibited an important degree of specificity since the isomer alpha-HCCH and endrin reproduced the same inhibitory pattern but beta-HCCH and dieldrin were inactive. Among various possibilities, the results suggest the modification of membrane fluidity by lindane and/or the activation of Ca2+-dependent protein kinase C by this compound leading to phosphorylation of Gs/adenylate cyclase. |
1(0,0,0,1) | Details |