| Name | FRAP |
|---|---|
| Synonyms | FK506 binding protein 12 rapamycin complex associated protein 1; FK506 binding protein 12 rapamycin associated protein 1; FKBP12 rapamycin complex associated protein 1; FKBP12 rapamycin complex associated protein; FRAP; FRAP 1; FRAP 2; FRAP1… |
| Name | dieldrin |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2446941 | Suter S, Trosko JE, el-Fouly MH, Lockwood LR, Koestner A: Dieldrin inhibition of gap junctional intercellular communication in rat glial cells as measured by the fluorescence photobleaching and scrape loading/dye transfer assays. Fundam Appl Toxicol. 1987 Nov;9(4):785-94. Application of the fluorescence-recovery after photobleaching (FRAP analysis) technique and scrape loading/dye transfer assay was made to measure the presence of gap junctional communication in primary rat glial cells in vitro in the presence and absence of the neurotoxicant and tumor promoter dieldrin, a chlorinated insecticide. |
62(0,2,2,2) | Details |
| 2197146 | Loch-Caruso R, Caldwell V, Cimini M, Juberg D: Comparison of assays for gap junctional communication using human embryocarcinoma cells exposed to dieldrin. Fundam Appl Toxicol. 1990 Jul;15(1):63-74. This assay was compared to assays for fluorescence return after photobleaching (FRAP), transfer of Lucifer yellow after scrape-loading, autoradiographic visualization of [3H]- nucleotide transfer, and metabolic coupling of 6-thioguanine (6-TG) metabolites. |
2(0,0,0,2) | Details |
| 8895858 | Matesic DF, Hayashi T, Trosko JE, Germak JA: Upregulation of gap junctional intercellular communication in immortalized gonadotropin-releasing hormone neurons by stimulation of the cyclic AMP pathway. Neuroendocrinology. 1996 Oct;64(4):286-97. A 24-hour treatment of GT1-7 neurons with 100 microM dibutyryl cAMP + 100 microM IBMX or with 2 microM forskolin increased by greater than 2-fold the percentage of cells that were dye coupled, using the noninvasive dye coupling assay, fluorescent recovery after photobleaching (FRAP). The increase in dye coupling induced by dibutyryl cAMP/IBMX was inhibited by or dieldrin, agents known to block gap junction-mediated intercellular coupling in other cell types. |
1(0,0,0,1) | Details |