Protein Information

Name aryl hydrocarbon receptor
Synonyms AHR; Ah receptor; AhR; Aryl hydrocarbon receptor; Aryl hydrocarbon receptor precursor; Dioxin receptor; Ah receptors; AhRs…

Compound Information

Name dieldrin
CAS

Reference List

PubMed Abstract RScore(About this table)
14636698 Long M, Laier P, Vinggaard AM, Andersen HR, Lynggaard J, Bonefeld-Jorgensen EC: Effects of currently used pesticides in the AhR-CALUX assay: comparison between the human TV101L and the rat H4IIE cell line. Toxicology. 2003 Dec 15;194(1-2):77-93.

We have used the AhR-CALUX assay to investigate the AhR-mediated activity of the persistent organochlorine insecticide dieldrin and twenty-two pesticides currently used in Denmark by employing the rat H4IIE and the human TV101L hepatoma cell lines.
86(1,1,1,6) Details
18767702 Lam JC, Murphy MB, Wang Y, Tanabe S, Giesy JP, Lam PK: Risk assessment of organohalogenated compounds in water bird eggs from South China. Environ Sci Technol. 2008 Aug 15;42(16):6296-302.

Organohalogen compounds, the pesticides aldrin, dieldrin, endrin, hexachlorobenzene, mirex, Sigmachlordanes, SigmaDDTs, Sigmaheptachlors, Sigmatoxaphenes, and the industrial chemicals SigmaPCBs and SigmaPBDEs, as well as total dioxin-like equivalents (TEQH4IIE-luc), were measured in eggs of two Ardeid species, the little egret (Egretta garzetta) and black-crowned night heron (Nycticorax nycticorax) from three port cities along the South China coast: Hong Kong, Xiamen, and Quanzhou.
Total concentrations of dioxin-like PCBtoxic equivalents (TEQs), measured as the aryl hydrocarbon receptor (AhR)-mediated responses of the H4IIE-luc bioassay (TEQH4IIE-luc), were greatest in Hong Kong samples.
1(0,0,0,1) Details
12193254 Oliver JD, Roberts RA: Receptor-mediated hepatocarcinogenesis: role of hepatocyte proliferation and apoptosis. Pharmacol Toxicol. 2002 Jul;91(1):1-7.


Dioxins and polychlorinated biphenyls bind to the aryl hydrocarbon receptor, phenobarbital binds to the constitutive androstane receptor and peroxisome proliferators act via the their activated receptor alpha.
1(0,0,0,1) Details