Protein Information

Name PARP
Synonyms COL11A2; PARP; Collagen alpha 2(XI) chain; Collagen alpha 2(XI) chain precursor; Collagen type XI alpha 2; Collagen type XI alpha 2 isoform 1; DFNA13; DFNB53…

Compound Information

Name dieldrin
CAS

Reference List

PubMed Abstract RScore(About this table)
15183012 Kitazawa M, Anantharam V, Kanthasamy A, Kanthasamy AG: Dieldrin promotes proteolytic cleavage of poly (ADP-ribose) polymerase and apoptosis in dopaminergic cells: protective effect of mitochondrial anti-apoptotic protein Bcl-2. Neurotoxicology. 2004 Jun;25(4):589-98.

Also, dieldrin (30-300 microM) treatment induced proteolytic cleavage of poly (ADP-ribose) polymerase (PARP), which was blocked by pretreatment with caspase-3 inhibitors Z-DEVD-FMK and Z-VAD-FMK.
81(1,1,1,1) Details