| Name | aspartate aminotransferase |
|---|---|
| Synonyms | Aspartate Aminotransferase 1; GIG18; GOT 1; GOT1; Aspartate aminotransferase; Glutamate oxaloacetate transaminase 1; Transaminase A; Aspartate aminotransferases… |
| Name | sulfur |
|---|---|
| CAS | sulfur |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19823174 | Sun Y, Tian Y, Prabha M, Liu D, Chen S, Zhang R, Liu X, Tang C, Tang X, Jin H, Du J: Effects of sulfur dioxide on hypoxic pulmonary vascular structural remodeling. Lab Invest. 2010 Jan;90(1):68-82. Epub 2009 Oct 12. For each group, we measured the pulmonary arterial pressure, sulfur dioxide content in plasma and lung tissue, glutamate oxaloacetate transaminase 1 and 2 mRNAs, micro- and ultra-structural changes in pulmonary arteries, proliferation of pulmonary smooth muscle cells, vascular collagen metabolism, pulmonary endothelial cell inflammatory response, and pulmonary vascular endothelin-1 production in the rats. |
31(0,1,1,1) | Details |
| 19762467 | Westrop GD, Georg I, Coombs GH: The mercaptopyruvate sulfurtransferase of Trichomonas vaginalis links catabolism to the production of thioredoxin persulfide. J Biol Chem. 2009 Nov 27;284(48):33485-94. Epub 2009 Sep 17. This consists of an aspartate aminotransferase (TvAspAT1), which transaminates to form (3-MP), and mercaptopyruvate sulfurtransferase (TvMST), which transfers the sulfur of 3-MP to a nucleophilic acceptor, generating |
31(0,1,1,1) | Details |
| 20306345 | Cooper AJ, Krasnikov BF, Niatsetskaya ZV, Pinto JT, Callery PS, Villar MT, Artigues A, Bruschi SA: Cysteine S-conjugate beta-lyases: important roles in the metabolism of naturally occurring sulfur and -containing compounds, xenobiotics and anticancer agents. Amino Acids. 2010 Mar 22. Here, we focus on more recent findings regarding: (1) the identification of enzymes associated with high-M (r) cysteine S-conjugate beta-lyases in the cytosolic and mitochondrial fractions of rat liver and kidney; (2) the mechanism of syncatalytic inactivation of rat liver mitochondrial aspartate aminotransferase by the nephrotoxic beta-lyase substrate S-(1,1,2,2-tetrafluoroethyl)-L: - (the S-conjugate of tetrafluoroethylene); (3) toxicant channeling of reactive fragments from the active site of mitochondrial aspartate aminotransferase to susceptible proteins in the mitochondria; (4) the involvement of cysteine S-conjugate beta-lyases in the metabolism/bioactivation of drugs and natural products; and (5) the role of cysteine S-conjugate beta-lyases in the metabolism of Se-conjugates. |
1(0,0,0,1) | Details |