Protein Information

Name Ca v
Synonyms CA V; CA VA; CA5; CA5A; CAV; CAVA; Carbonate dehydratase VA; Carbonic anhydrase V…

Compound Information

Name sulfur
CAS sulfur

Reference List

PubMed Abstract RScore(About this table)
19369579 Horak S, Koschak A, Stuppner H, Striessnig J: Use-dependent block of voltage-gated Cav2.1 Ca2+ channels by petasins and eudesmol isomers. J Pharmacol Exp Ther. 2009 Jul;330(1):220-6. Epub 2009 Apr 15.

We demonstrate that S-petasin, iso-S-petasin, and eudesmol are Ca (v) 2.1 channel inhibitors preferentially acting as use-dependent channel blockers and with the sulfur-containing substituent in position 3 of the petasins serving as important functional feature.
116(1,2,2,6) Details