Protein Information

Name CA1
Synonyms CA IX; CA1; Carbonic anhydrase I; CA2; CAII; Carbonic anhydrase II; Carbonic dehydratase; Carbonic anhydrase III…

Compound Information

Name lindane
CAS (1α,2α,3β,4α,5α,6β)-1,2,3,4,5,6-hexachlorocyclohexane

Reference List

PubMed Abstract RScore(About this table)
7566682 Joy RM, Walby WF, Stark LG, Albertson TE: Lindane blocks GABAA-mediated inhibition and modulates pyramidal cell excitability in the rat hippocampal slice. Neurotoxicology. 1995 Summer;16(2):217-28.

An in vitro paired-pulse orthodromic stimulation technique was used to examine the effects of lindane on excitatory afferent terminals, CA1 pyramidal cells and recurrent collateral evoked inhibition in the rat hippocampal slice.
32(0,1,1,2) Details
9291495 Albertson TE, Walby WF, Stark LG, Joy RM: The effects of lindane and long-term potentiation (LTP) on pyramidal cell excitability in the rat hippocampal slice. Neurotoxicology. 1997;18(2):469-77.

An in vitro orthodromic stimulation technique was used to examine the effects of lindane and long-term potentiation (LTP) inducing stimuli, alone or in combination, on the excitatory afferent terminal of CA1 pyramidal cells and on recurrent collateral evoked inhibition using the rat hippocampal slice model.
32(0,1,1,2) Details
7533233 Planas AM, Soriano MA, Ferrer I, Rodriguez Farre E: Regional expression of inducible heat shock protein-70 mRNA in the rat brain following administration of convulsant drugs. Brain Res Mol Brain Res. 1994 Nov;27(1):127-37.

Expression of inducible heat shock protein-70 mRNA (hsp-70 mRNA) was studied in the rat brain following systemic administration of different convulsant agents: an L-type voltage-dependent calcium channel agonist, (+/-)-BAY K 8644 (BAY-K); the excitotoxic glutamate agonists kainic acid and N-methyl-D-aspartic acid (NMDA); and the GABAA receptor complex antagonists pentylenetetrazole (PTZ) and lindane (gamma-hexaclorocyclohexane).
Expression was localized in select cerebral regions, notably the pyramidal cell layer of the hippocampal CA3 field of Ammon's horn and the piriform cortex, and also the subicular complex and the amygdala, and, to a lesser extent, the entorhinal cortex, the pyramidal cell layer of CA1, several thalamic nuclei, and the parietal cortex.
2(0,0,0,2) Details