| Name | FMO3 |
|---|---|
| Synonyms | Dimethylaniline monooxygenase [N oxide forming] 3; Dimethylaniline oxidase 3; FMO 3; FMO II; FMO form 2; FMO3; FMOII; Flavin containing monooxygenase 3… |
| Name | fenthion |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 14976351 | Furnes B, Schlenk D: Evaluation of xenobiotic N- and S-oxidation by variant flavin-containing monooxygenase 1 (FMO1) enzymes. Toxicol Sci. 2004 Apr;78(2):196-203. Epub 2004 Feb 19. FMO3 metabolized fenthion to its sulfoxide at a lower catalytic efficiency than FMO1 (27%) and with less stereoselectivity (74% (+)-sulfoxide). |
81(1,1,1,1) | Details |
| 15547051 | Furnes B, Schlenk D: Extrahepatic metabolism of and organophosphate thioether compounds by the flavin-containing monooxygenase and cytochrome P450 systems. Drug Metab Dispos. 2005 Feb;33(2):214-8. Epub 2004 Nov 16. The relative contribution of FMO1 and FMO3 to the sulfoxidation of carbophenothion, demeton-O, ethiofencarb, fonofos, and methiocarb also was investigated by using baculovirus-expressed recombinant proteins. Stereoselective sulfoxidation of fenthion and methiocarb by human liver, kidney, and microsomes was investigated. |
1(0,0,0,1) | Details |