| 20087863 |
Yu ZY, Huang R, Xiao H, Sun WF, Shan YJ, Wang B, Zhao TT, Dong B, Zhao ZH, Liu XL, Wang SQ, Yang RF, Luo QL, Cong YW: Fluacrypyrim, a novel STAT3 activation inhibitor, induces cell cycle arrest and apoptosis in cancer cells harboring constitutively-active STAT3. Int J Cancer. 2010 Jan 19.
Herein, we demonstrate that a novel small molecule fluacrypyrim (FAPM) inhibits the growth of leukemia cells by a predominant G1 arrest with significant decrease of the protein and mRNA levels of cyclin D1. |
82(1,1,1,2) |
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