Protein Information

Name keratin (protein family or complex)
Synonyms Keratin; Keratins

Compound Information

Name sulfur
CAS sulfur

Reference List

PubMed Abstract RScore(About this table)
19897662 Na N, Chandel NS, Litvan J, Ridge KM: Mitochondrial reactive oxygen species are required for hypoxia-induced degradation of keratin intermediate filaments. FASEB J. 2010 Mar;24(3):799-809. Epub 2009 Nov 6.

6(0,0,0,6) Details
19822360 Hill P, Brantley H, Van Dyke M: Some properties of keratin biomaterials: kerateines. Biomaterials. 2010 Feb;31(4):585-93. Epub 2009 Oct 12.

Numerous methods exist for denaturing these proteins which are characterized by a high sulfur content and extensive disulfide bonding, under either oxidative or reductive conditions, extracting them from tissue and processing them into various physical states such as gels, films, coatings, and fibers.
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19455514 El-Sayed AS: L-methioninase production by Aspergillus flavipes under solid-state fermentation. J Basic Microbiol. 2009 Aug;49(4):331-41.


The enzyme preparation has a broad substrate spectrum showing a higher affinity to deaminate L-glycine, N -acetylglucosamine and glutamic acid, in addition to their proteolytic activity against bovine serum albumin, casein, gelatin and keratin.
1(0,0,0,1) Details
19542129 Kublanov IV, Bidjieva SKh, Mardanov AV, Bonch-Osmolovskaya EA: Desulfurococcus kamchatkensis sp. nov., a novel hyperthermophilic protein-degrading archaeon isolated from a Kamchatka hot spring. Int J Syst Evol Microbiol. 2009 Jul;59(Pt 7):1743-7. Epub 2009 Jun 19.

The isolate fermented a wide range of substrates including proteins: alpha-keratin, albumin and gelatin.
Elemental sulfur was not essential for growth, but stimulated growth.
1(0,0,0,1) Details
19843334 Saari SA, Juuti KH, Palojarvi JH, Vaisanen KM, Rajaniemi RL, Saijonmaa-Koulumies LE: Demodex gatoi-associated contagious pruritic dermatosis in cats--a report from six households in Finland. Acta Vet Scand. 2009 Oct 20;51:40.


It possesses a distinct stubby appearance, and, instead of residing in the hair follicles, it dwells in the keratin layer of the epidermis, causing a pruritic and contagious skin disease in cats.
1(0,0,0,1) Details