Protein Information

Name AKR1A1
Synonyms AKR1A1; ALR; AKR1A1 protein; ALDR 1; ALDR1; Alcohol dehydrogenase [NADP+]; Aldehyde reductase; Aldo keto reductase family 1 member A1…

Compound Information

Name diflubenzuron
CAS

Reference List

PubMed Abstract RScore(About this table)
16411658 Jiang H, Vudathala DK, Blair IA, Penning TM: Competing roles of aldo-keto reductase 1A1 and cytochrome P4501B1 in benzo [a] pyrene-7,8-diol activation in human bronchoalveolar H358 cells: role of AKRs in P4501B1 induction. Chem Res Toxicol. 2006 Jan;19(1):68-78.

P4501B1 induction was blocked in AKR1A1 transfectants by the AKR1A1 inhibitor (sulfonylnitromethane), the o-quinone scavenger (N-acetyl-l-cysteine), or the cytosolic AhR antagonist (diflubenzuron).
36(0,1,1,6) Details