Protein Information

Name glutathione S transferases
Synonyms GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2…

Compound Information

Name diflubenzuron
CAS

Reference List

PubMed Abstract RScore(About this table)
18627795 Pereira Maduenho L, Martinez CB: Acute effects of diflubenzuron on the freshwater fish Prochilodus lineatus. Comp Biochem Physiol C Toxicol Pharmacol. 2008 Sep;148(3):265-72. Epub 2008 Jun 26.

The induction of glutathione-S-transferase (GST) and catalase activities in liver pointed to the activation of xenobiotic metabolic pathways and antioxidant defenses.
1(0,0,0,1) Details
17665366 Reyes M, Franck P, Charmillot PJ, Ioriatti C, Olivares J, Pasqualini E, Sauphanor B: Diversity of insecticide resistance mechanisms and spectrum in European populations of the codling moth, Cydia pomonella. Pest Manag Sci. 2007 Sep;63(9):890-902.

Resistances to azinphos-methyl, diflubenzuron, spinosad, tebufenozide and thiacloprid were significantly correlated with mixed-function oxidase activity, while increased glutathione-S-transferase and reduced non-specific esterase activities were correlated with resistance to azinphos-methyl and emamectin, respectively.
81(1,1,1,1) Details
11033162 Feng Q, Davey KG, S D Pang A, Ladd TR, Retnakaran A, Tomkins BL, Zheng S, Palli SR: Developmental expression and stress induction of glutathione S-transferase in the spruce budworm, Choristoneura fumiferana. J Insect Physiol. 2001 Jan 1;47(1):1-10.

The bacterial insecticide, Bacillus thuringiensis delta-endotoxin (Bt), the non-steroidal ecdysone analog, tebufenozide, and the synthetic pyrethroid, permethrin, induced the expression of CfGST mRNA in 5th instar larvae, whereas the chitin synthesis inhibitor, diflubenzuron, did not have any such effect.
2(0,0,0,2) Details
12232873 Bouvier JC, Boivin T, Beslay D, Sauphanor B: Age-dependent response to insecticides and enzymatic variation in susceptible and resistant codling moth larvae. Arch Insect Biochem Physiol. 2002 Oct;51(2):55-66.

The aim of this study was to follow the age variations in larval susceptibility to deltamethrin and teflubenzuron in one susceptible (S) strain, and two resistant (Rv and Rt) ones selected for resistance to deltamethrin and diflubenzuron, respectively.
The age variation of the activities of cytochrome P450-dependent monooxygenase (MFO), glutathione S-transferases (GST), and esterases in S and both resistant strains were simultaneously investigated.
1(0,0,0,1) Details
3095414 Young MF, Trombetta LD, Carson S: Effects of diflubenzuron on the mouse liver. . J Appl Toxicol. 1986 Oct;6(5):343-8.

Hepatic glutathione S-transferase activity as well as morphological characteristics were studied.
2(0,0,0,2) Details
12522433 Boivin T, Bouvier JC, Chadoeuf J, Beslay D, Sauphanor B: Constraints on adaptive mutations in the codling moth Cydia pomonella (L.): measuring fitness trade-offs and natural selection. Heredity. 2003 Jan;90(1):107-13.


The selective coefficients were also estimated for both the major cytochrome P450-dependent monooxygenase (MFO) and the minor glutathione S-transferase (GST) systems (0.17 and negligible, respectively), which have been previously shown to be involved in resistance.
1(0,0,0,1) Details