Protein Information

Name methionine synthase
Synonyms 5 methyltetrahydrofolate homocysteine methyltransferase; 5 methyltetrahydrofolate homocysteine S methyltransferase; 5 methyltetrahydrofolate homocysteine methyltransferase; MS; MTR; Methionine synthase; Tetrahydropteroylglutamate methyltransferase; 5 methyltetrahydrofolate homocysteine S methyltransferases…

Compound Information

Name sulfur
CAS sulfur

Reference List

PubMed Abstract RScore(About this table)
19827815 Alonso H, Cummins PL, Gready JE: Methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase (MeTr): protonation state of the ligand and active-site residues. J Phys Chem B. 2009 Nov 5;113(44):14787-96.

Methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase (MeTr) catalyzes the transfer of the N5-methyl group from N5-methyltetrahydrofolate (CH (3) THF) to the cobalt center of a corrinoid/iron-sulfur protein, a reaction similar to that of cobalamin-dependent methionine synthase (MetH).
31(0,1,1,1) Details
19724160 Petramala L, Acca M, Francucci CM, D'Erasmo E: Hyperhomocysteinemia: a biochemical link between bone and cardiovascular system diseases?. J Endocrinol Invest. 2009;32(4 Suppl):10-4.

Homocysteine (HCY) is a sulfur-containing amino acid involved in two metabolic pathways, catalized by cystathionine-B-synthase and methionine synthase, depending on vitamin (vit) B6, B12, and folate levels and enzymatic activity of methylenetetrahydrofolate.
6(0,0,1,1) Details