| Name | CYP51 |
|---|---|
| Synonyms | CP51; CYPL 1; CYPL1; CYP51; CYP51A1; CYPLI; Cytochrome P450 51A1; LDM… |
| Name | epoxiconazole |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16989930 | Trosken ER, Adamska M, Arand M, Zarn JA, Patten C, Volkel W, Lutz WK: Comparison of lanosterol-14 alpha-demethylase (CYP51) of human and Candida albicans for inhibition by different antifungal azoles. Toxicology. 2006 Nov 10;228(1):24-32. Epub 2006 Aug 12. The most favourable IC (50) ratio human to Candida was observed for imazalil (440-fold), while the specificity of epoxiconazole and tebuconazole for cCYP51 was only by a factor of 10. |
4(0,0,0,4) | Details |
| 15276168 | Trosken ER, Straube E, Lutz WK, Volkel W, Patten C: Quantitation of and its major metabolite FF-MAS in an inhibition assay of CYP51 by azoles with atmospheric pressure photoionization based LC-MS/MS. J Am Soc Mass Spectrom. 2004 Aug;15(8):1216-21. IC (50) values of epoxiconazole and miconazole-two widely used azole fungicides used in agriculture and in human medicine, respectively-were 1.95 microM and 0.057 microM. |
4(0,0,0,4) | Details |