Protein Information

Name cytochrome c 1
Synonyms CYC 1; CYC1; Cytochrome C1; Cytochrome c 1; Cytochrome C1s; Cytochrome c 1s

Compound Information

Name famoxadone
CAS 5-methyl-5-(4-phenoxyphenyl)-3-(phenylamino)-2,4-oxazolidinedione

Reference List

PubMed Abstract RScore(About this table)
12525495 Xiao K, Engstrom G, Rajagukguk S, Yu CA, Yu L, Durham B, Millett F: Effect of famoxadone on photoinduced electron transfer between the iron-sulfur center and cytochrome c1 in the cytochrome bc1 complex. J Biol Chem. 2003 Mar 28;278(13):11419-26. Epub 2003 Jan 13.
31(0,1,1,1) Details
15708371 Pember SO, Fleck LC, Moberg WK, Walker MP: Mechanistic differences in inhibition of ubiquinol cytochrome c reductase by the proximal Qo-site inhibitors famoxadone and methoxyacrylate stilbene. Arch Biochem Biophys. 2005 Mar 15;435(2):280-90.

Since both inhibitors bind within the proximal niche, the formation of an ESI complex implicates substrate binding within the distal niche near the iron-sulfur protein (ISP) and cytochrome c (1) (C1).
1(0,0,0,1) Details