| Name | cholinesterases |
|---|---|
| Synonyms | Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase… |
| Name | isofenphos |
|---|---|
| CAS | 1-methylethyl 2-[[ethoxy[(1-methylethyl)amino]phosphinothioyl]oxy]benzoate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9891917 | Astroff AB, Young AD: The relationship between maternal and fetal effects following maternal organophosphate exposure during gestation in the rat. Toxicol Ind Health. 1998 Nov-Dec;14(6):869-89. This study compared the maternal and fetal effects, including cholinesterase inhibition, following gestational exposure to six organophosphates: tribufos, oxydemeton-methyl, azinphos-methyl, fenamiphos, isofenphos, and fenthion in the Sprague-Dawley rat. |
86(1,1,1,6) | Details |
| 15234572 | Williams RD, Boros LG, Kolanko CJ, Jackman SM, Eggers TR: Chromosomal aberrations in human lymphocytes exposed to the anticholinesterase pesticide isofenphos with mechanisms of leukemogenesis. Leuk Res. 2004 Sep;28(9):947-58. |
13(0,0,2,3) | Details |
| 10771584 | Nigg HN, Knaak JB: Blood cholinesterases as human biomarkers of organophosphorus pesticide exposure. Rev Environ Contam Toxicol. 2000;163:29-111. OPs possessing carboxylesters, such as malathion and isofenphos, are hydrolyzed by the direct action of 'B'-esterases (i.e., carboxylesterase, CaE). |
2(0,0,0,2) | Details |
| 6510327 | Hill EF, Camardese MB: Toxicity of anticholinesterase insecticides to birds: technical grade versus granular formulations. Ecotoxicol Environ Saf. 1984 Dec;8(6):551-63. The test chemicals were Amaze 15G (isofenphos), Counter 15G (terbufos), Dasanit 15G (fensulfothion), Diazinon 14G (diazinon), Di-Syston 15G (disulfoton), Dyfonate 20G (fonofos), Furadan 10G (carbofuran), Lorsban 15G (chlorpyrifos), Nemacur 15G (fenamiphos), Parathion 10G (parathion), Tattoo 10G (bendiocarb), Temik 15G (aldicarb), and Thimet 15G (phorate). |
2(0,0,0,2) | Details |
| 1566275 | Henderson JD, Higgins RJ, Dacre JC, Wilson BW: Neurotoxicity of acute and repeated treatments of tabun, paraoxon, diisopropyl fluorophosphate and isofenphos to the hen. Toxicology. 1992;72(2):117-29. Plasma acetylcholinesterase (AChE), non-specific butyrylcholinesterase (BChE) and kinase (CK) activities were measured in order to monitor whether the compounds were present at biologically active concentrations. |
1(0,0,0,1) | Details |
| 10048710 | Calore EE, Sesso A, Puga FR, Cavaliere MJ, Calore NM, Weg R: Sarcoplasmic lipase and non-specific esterase inhibition in myofibers of rats intoxicated with the organophosphate isofenphos. Exp Toxicol Pathol. 1999 Jan;51(1):27-33. This sarcoplasmic inhibition of esterases occurs roughly in parallel to the inhibition of plasma cholinesterase activity. |
1(0,0,0,1) | Details |
| 9711194 | Cavaliere MJ, Puga FR, Calore EE, Calore NM, Pelegrino JR, da Rosa AR, Weg R: Protective effect of pralidoxime on muscle fiber necrosis induced by organophosphate compounds. J Toxicol Clin Toxicol. 1998;36(4):295-300. CONCLUSIONS: Oxime reduced diaphragmatic muscle necrosis in experimental organophosphate intoxication, despite little effect on plasma cholinesterase. DESIGN: Adult male Wistar rats were given oral organophosphate compounds dissolved in formal: dichlorvos, isofenphos, metamidophos, and diazinon. |
1(0,0,0,1) | Details |
| 15112752 | Knaak JB, Dary CC, Power F, Thompson CB, Blancato JN: Physicochemical and biological data for the development of predictive organophosphorus pesticide QSARs and PBPK/PD models for human risk assessment. Crit Rev Toxicol. 2004 Mar-Apr;34(2):143-207. Except for work on parathion, chlorpyrifos, and isofenphos, very few modeling data were found on the 31 OPs of interest. A limited amount of acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and carboxylesterase (CaE) inhibition and recovery data were found in the literature on the 31 OPs. |
1(0,0,0,1) | Details |