Protein Information

Name mitogen activated protein kinase (protein family or complex)
Synonyms MAPK; mitogen activated protein kinase; mitogen activated protein kinases

Compound Information

Name kinetin
CAS

Reference List

PubMed Abstract RScore(About this table)
8947491 Patel V, Brown C, Goodwin A, Wilkie N, Boarder MR: Phosphorylation and activation of p42 and p44 mitogen-activated protein kinase are required for the P2 purinoceptor stimulation of endothelial prostacyclin production. Biochem J. 1996 Nov 15;320 ( Pt 1):221-6.

6(0,0,0,6) Details
9398433 Eckberg WR: MAP and cdc2 kinase activities at germinal vesicle breakdown in Chaetopterus. Dev Biol. 1997 Nov 15;191(2):182-90.


In frog oocytes, activation of mitogen-activated protein kinase (MAPK, ERK) leads to activation of cdc2 and germinal vesicle breakdown (GVBD).
6(0,0,0,6) Details
9523556 Maas JW Jr, Horstmann S, Borasio GD, Anneser JM, Shooter EM, Kahle PJ: Apoptosis of central and peripheral neurons can be prevented with cyclin-dependent kinase/mitogen-activated protein kinase inhibitors. J Neurochem. 1998 Apr;70(4):1401-10.

3(0,0,0,3) Details
15331628 Chan WK, Dickerson A, Ortiz D, Pimenta AF, Moran CM, Motil J, Snyder SJ, Malik K, Pant HC, Shea TB: Mitogen-activated protein kinase regulates neurofilament axonal transport. . J Cell Sci. 2004 Sep 15;117(Pt 20):4629-42. Epub 2004 Aug 25.

2(0,0,0,2) Details
14654224 Ishii Y, Sakai S, Honma Y: Cytokinin-induced differentiation of human myeloid leukemia HL-60 cells is associated with the formation of nucleotides, but not with incorporation into DNA or RNA. Biochim Biophys Acta. 2003 Dec 7;1643(1-3):11-24.

Cytokinins such as isopentenyladenine (IPA), kinetin and benzyladenine were very effective at inducing the granulocytic differentiation of human myeloid leukemia HL-60 cells.
Cytokinins effectively induced a phosphorylated (active) form of mitogen-activated protein kinase (MAPK).
2(0,0,0,2) Details
9779816 Cheng TJ, Lai YK: Identification of mitogen-activated protein kinase-activated protein kinase-2 as a vimentin kinase activated by okadaic acid in 9L rat brain tumor cells. J Cell Biochem. 1998 Nov 1;71(2):169-81.


With specific protein kinase inhibitors, we show the possible involvement of the cdc2 kinase- and p38 mitogen-activated protein kinase (p38MAPK)-mediated pathways in this process.
1(0,0,0,1) Details
9753691 Wang Z, Canagarajah BJ, Boehm JC, Kassisa S, Cobb MH, Young PR, Abdel-Meguid S, Adams JL, Goldsmith EJ: Structural basis of inhibitor selectivity in MAP kinases. Structure. 1998 Sep 15;6(9):1117-28.


BACKGROUND: The mitogen-activated protein (MAP) kinases are important signaling molecules that participate in diverse cellular events and are potential targets for intervention in inflammation, cancer, and other diseases.
1(0,0,0,1) Details
9792443 Forrer P, Tamaskovic R, Jaussi R: Enzyme-linked immunosorbent assay for measurement of JNK, ERK, and p38 kinase activities. Biol Chem. 1998 Aug-Sep;379(8-9):1101-11.


A rapid enzyme-linked immunosorbent assay for the enzyme activity measurement of three well-known mitogen-activated protein (MAP) kinases, JNK2, ERK2, and p38 is described.
1(0,0,0,1) Details