Protein Information

Name demethylases
Synonyms DMTase; Demethylase; MBD 2; MBD2; Methyl CpG binding domain protein 2; Methyl CpG binding protein MBD2; NY CO 41; Demethylases…

Compound Information

Name linuron
CAS

Reference List

PubMed Abstract RScore(About this table)
7823289 Scassellati-Sforzolini G, Moretti M, Villarini M, Monarca S, Fatigoni C, Pasquini R: In vivo studies on enzymatic induction activity of Linuron. . J Environ Pathol Toxicol Oncol. 1994;13(1):11-7.

A reduction in the aminopyrine N-demethylase activity was noted for the highest dose of pure Linuron, whereas an increment in this activity was observed for all the doses of the commercial preparation tested.
37(0,1,2,2) Details
9990096 Siminszky B, Corbin FT, Ward ER, Fleischmann TJ, Dewey RE: Expression of a soybean cytochrome P450 monooxygenase cDNA in yeast and tobacco enhances the metabolism of phenylurea herbicides. Proc Natl Acad Sci U S A. 1999 Feb 16;96(4):1750-5.

Analyses of the metabolites suggest that the CYP71A10 encoded enzyme functions primarily as an N-demethylase with regard to fluometuron, linuron, and diuron, and as a ring-methyl hydroxylase when chlortoluron is the substrate.
31(0,1,1,1) Details
4709869 Bankowska J, Bojanowska A: [Distribution of the activity of demethylases in some fractions of rat liver cells exposed previously to urea herbicides] Rocz Panstw Zakl Hig. 1973;24(1):93-100.

1(0,0,0,1) Details