| Name | cholinesterase |
|---|---|
| Synonyms | Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase… |
| Name | methidathion |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18072155 | Mohammad FK, Alias AS, Ahmed OA: Electrometric measurement of plasma, erythrocyte, and whole blood cholinesterase activities in healthy human volunteers. J Med Toxicol. 2007 Mar;3(1):25-30. Using the modified electrometric method, various percentages of cholinesterase inhibitions in the plasma, erythrocytes, and whole blood were detected after in vitro addition of the organophosphate insecticides (chlorpyrifos and methidathion) and the insecticide (carbaryl) to the reaction mixtures. |
47(0,1,2,12) | Details |
| 2259753 | Quest JA, Copley MP, Hamernik KL, Rinde E, Fisher B, Engler R, Burnam WL, Fenner-Crisp PA: Evaluation of the carcinogenic potential of pesticides. 2. Regul Toxicol Pharmacol. 1990 Oct;12(2):117-26. The carcinogen potential of methidathion, a dimethoxyorganic pesticide and cholinesterase inhibitor, was evaluated by the Health Effects Division of the Office of Pesticide Programs using a consensus peer review process and the EPA's guidelines for risk assessment. |
31(0,1,1,1) | Details |
| 94259 | Hart RJ, Cavey WA, Moore B, Strong MB: Efficiency and safety of methidathion applied as a pour-on systemic insecticide for control of cattle lice. Aust Vet J. 1979 Dec;55(12):575-9. Treatment with fenthion at 50 mg/kg, 7.4 times the average recommended rate, famphur at 75 mg/kg, 3 times the average rate and chlorpyrifos at 85 mg/kg, 5 times average rate, caused reductions in whole blood cholinesterase activity of 52%, 27% and 47% respectively which were similar to the reductions in cholinesterase activity found in calves treated with methidathion at similar levels above the recommended commercial dose rates. |
6(0,0,1,1) | Details |
| 9195193 | Lang G, Kufcsak O, Szegletes T, Nemcsok J: Quantitative distributions of different cholinesterases and inhibition of acetylcholinesterase by metidathion and paraquat in alimentary canal of common carp. Gen Pharmacol. 1997 Jul;29(1):55-9. |
3(0,0,0,3) | Details |
| 16583303 | Sutcu R, Altuntas I, Yildirim B, Karahan N, Demirin H, Delibas N: The effects of subchronic methidathion toxicity on rat liver: role of antioxidant vitamins C and E. Cell Biol Toxicol. 2006 May;22(3):221-7. Subchronic MD exposure was evaluated for its effects on lipid peroxidation, the serum activities of cholinesterase (ChE), and enzymes concerning liver damage, and the protective effects of combination of vitamins E and C in albino rats. |
2(0,0,0,2) | Details |
| 15311849 | Yavuz T, Altuntas I, Delibas N, Yildirim B, Candir O, Cora A, Karahan N, Ibrisim E, Kutsal A: Cardiotoxicity in rats induced by methidathion and ameliorating effect of vitamins E and C. Hum Exp Toxicol. 2004 Jul;23(7):323-9. An autoanalyser was used to determine the serum activities of cholinesterase (ChE). |
1(0,0,0,1) | Details |
| 1375147 | Szabo A, Nemcsok J, Asztalos B, Rakonczay Z, Kasa P, Hieu LH: The effect of pesticides on carp (Cyprinus carpio L). Ecotoxicol Environ Saf. 1992 Feb;23(1):39-45. Tissue AChE activity was determined in response to specific inhibitors (ethopropazine, BW 284 C51) or pesticides (CuSO4, paraquat (PQ), methidathion (MD)). Experiments with specific choline esterase inhibitors revealed a very low amount of pseudocholinesterase in all tissues studied. |
1(0,0,0,1) | Details |
| 1516789 | Chang JC, Walberg JA, Campbell WR: One-year dietary toxicity study with methidathion in beagle dogs. Fundam Appl Toxicol. 1992 Aug;19(2):307-14. Major treatment-related effects were cholestasis, chronic inflammation in the liver, and cholinesterase (ChE) inhibition. |
1(0,0,0,1) | Details |
| 17698944 | Guney M, Demirin H, Oral B, Ozguner M, Bayhan G, Altuntas I: Ovarian toxicity in rats caused by methidathion and ameliorating effect of vitamins E and C. Hum Exp Toxicol. 2007 Jun;26(6):491-8. Serum malondialdehyde (MDA: an indicator of lipid peroxidation) concentration, serum activity of cholinesterase (ChE), and ovary histopathology were studied. |
1(0,0,0,1) | Details |
| 12185416 | Altuntas I, Delibas N, Demirci M, Kilinc I, Tamer N: The effects of methidathion on lipid peroxidation and some liver enzymes: role of vitamins E and C. Arch Toxicol. 2002 Aug;76(8):470-3. Epub 2002 May 29. We have, therefore, examined the in vivo and in vitro effects of MD on the serum activities of cholinesterase (ChE), enzymes concerning liver damage and lipid peroxidation (LPO; only in vivo), and have evaluated the ameliorating effects of a combination of vitamins E and C against MD toxicity. |
1(0,0,0,1) | Details |
| 19949736 | Kang EJ, Seok SJ, Lee KH, Gil HW, Yang JO, Lee EY, Hong SY: Factors for determining survival in acute organophosphate poisoning. Korean J Intern Med. 2009 Dec;24(4):362-7. Epub 2009 Nov 27. However, other organophosphates showed different mortality (16.7% for O-ethyl-O- phenylphosphonothioate, 25% for phenthoate, 37.5% for phosphamidon, 50% for methidathion). We investigated patient survival according to initial parameters, including the initial Acute Physiology and Chronic Health Evaluation (APACHE) II score, serum cholinesterase level, and hemoperfusion and evaluated the mortality according to organophosphate types. |
1(0,0,0,1) | Details |
| 8693683 | Tsatsakis AM, Aguridakis P, Michalodimitrakis MN, Tsakalov AK, Alegakis AK, Koumantakis E, Troulakis G: Experiences with acute organophosphate poisonings in Crete. Vet Hum Toxicol. 1996 Apr;38(2):101-7. Significant fluctuations of the plasma cholinesterase activity were observed during therapy. Considerable pesticide was measured in testis (eg 5.8 micrograms fenthion/g, 0.8 micrograms methidathion/g) and uterus (170.5 micrograms malathion/g). |
1(0,0,0,1) | Details |
| 1650168 | Drevenkar V, Radic Z, Vasilic Z, Reiner E: Dialkylphosphorus metabolites in the urine and activities of esterases in the serum as biochemical indices for human absorption of organophosphorus pesticides. Arch Environ Contam Toxicol. 1991 Apr;20(3):417-22. Ninety-seven agricultural workers were monitored for absorption of the organophosphorus pesticides methidathion, vamidothion, and azinphos-methyl, which were sprayed in an orchard during two seasons. This study confirmed that dialkylphosphorus metabolites in the urine are a more sensitive index of absorption than cholinesterase inhibition in the serum but lack of correlation between cholinesterase inhibition and metabolite concentration indicates that both parameters should be monitored. |
1(0,0,0,1) | Details |