Protein Information

Name glutathione S transferase
Synonyms GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2…

Compound Information

Name methomyl
CAS

Reference List

PubMed Abstract RScore(About this table)
18850358 Garg DP, Kiran R, Bansal AK, Malhotra A, Dhawan DK: Role of vitamin E in mitigating methomyl induced acute toxicity in blood of male Wistar rats. Drug Chem Toxicol. 2008;31(4):487-99.

The effects of different treatments were studied on lipid peroxidation (LPO), reduced glutathione (GSH) and antioxidant enzymes, which included superoxide dismutase (SOD), glutathione-s-transferase (GST), glutathione reductase (GR), glutathione peroxidase (GSHPx) and catalase and various hematological parameters, including total leucocytes count (TLC), differential leukocyte count (DLC), hemoglobin, platelets counts, red cell counts, and scanning electron microscopy (SEM).
1(0,0,0,1) Details
19825863 Mansour SA, Mossa AT, Heikal TM: Effects of methomyl on lipid peroxidation and antioxidant enzymes in rat erythrocytes: in vitro studies. Toxicol Ind Health. 2009 Sep;25(8):557-63.

The results showed that methomyl decreased acetylcholinesterase (AChE), superoxide dismutase (SOD) and glutathione S-transferase (GST) activities and increased level of lipid peroxidation (LPO) as well as the percentage of haemolysis.
6(0,0,1,1) Details
18665458 Li H, Jiang H, Gao X, Wang X, Qu W, Lin R, Chen J: Acute toxicity of the pesticide methomyl on the topmouth gudgeon (Pseudorasbora parva): mortality and effects on four biomarkers. Fish Physiol Biochem. 2008 Sep;34(3):209-16. Epub 2007 Aug 27.

In this study, the acute toxicity of the pesticide methomyl on the topmouth gudgeon (Pseudorasbora parva) was evaluated using mortality and the activity of the enzymes acetylcholinesterase (AChE), glutathione S-transferases (GSTs), glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT) as endpoints.
6(0,0,1,1) Details
16669347 El-Khawaga OA: Role of selenium on antioxidant capacity in methomyl-treated mice. J Physiol Biochem. 2005 Dec;61(4):501-6.

The antioxidant capacity of hepatic cells in terms of the activities of superoxide dismutase (SOD), catalase (CAT), glutathione reductase (GR), glutathione-S-transferase (GST) and glutathione (GSH) content was diminished.
1(0,0,0,1) Details
11886776 Tsagkarakou A, Pasteur N, Cuany A, Chevillon C, Navajas M: Mechanisms of resistance to organophosphates in Tetranychus urticae (Acari: Tetranychidae) from Greece. Insect Biochem Mol Biol. 2002 Apr;32(4):417-24.


We investigated the mechanisms conferring resistance to methyl-parathion (44-fold) and to methomyl (8-fold) in Tetranychus urticae from Greece by studying the effect of synergists on the resistance and the kinetic characteristics of various enzymes in a resistant strain (RLAB) and a susceptible reference strain (SAMB).
0(0,0,0,0) Details
12558102 Pree DJ, Whitty KJ, Bittner LA, Pogoda MK: Mechanisms of resistance to organophosphorus insecticides in populations of the obliquebanded leafroller Choristoneura rosaceana (Harris) (Lepidoptera: Tortricidae) from southern Ontario. Pest Manag Sci. 2003 Jan;59(1):79-84.


Resistance extended to methyl carbamates and to methomyl.
0(0,0,0,0) Details