Protein Information

Name GAL4
Synonyms Antigen NY CO 27; GAL 4; GAL4; Galectin 4; L 36 lactose binding protein; L36LBP; LGALS 4; LGALS4…

Compound Information

Name methoprene
CAS

Reference List

PubMed Abstract RScore(About this table)
18252248 Barry J, Wang S, Wilson TG: Overexpression of Methoprene-tolerant, a Drosophila melanogaster gene that is critical for juvenile hormone action and insecticide resistance. Insect Biochem Mol Biol. 2008 Mar;38(3):346-53. Epub 2007 Dec 7.

When expression of transgenic UAS-Met+ was driven to high levels by either an actin-GAL4 or tubulin-GAL4 promoter, larvae showed high mortality in the absence of methoprene, indicating that high MET titer is lethal, perhaps resulting from expression in an inappropriate tissue.
6(0,0,1,1) Details
15720391 Miura K, Oda M, Makita S, Chinzei Y: Characterization of the Drosophila Methoprene -tolerant gene product. FEBS J. 2005 Mar;272(5):1169-78.

In transient transfection assays using Drosophila S2 cells the yeast GAL4-DNA binding domain fused to MET exerted JH- or JHA-dependent activation of a reporter gene.
1(0,0,0,1) Details