Protein Information

Name CYP2A6
Synonyms CPA 6; CPA6; Flavoprotein linked monooxygenase; CYP2A; P450C2A; P450PB; CYP2A3; CYP2A6…

Compound Information

Name methoxychlor
CAS 1,1′-(2,2,2-trichloroethylidene)bis[4-methoxybenzene]

Reference List

PubMed Abstract RScore(About this table)
9733665 Stresser DM, Kupfer D: Human cytochrome P450-catalyzed conversion of the proestrogenic pesticide methoxychlor into an estrogen. Drug Metab Dispos. 1998 Sep;26(9):868-74.

Co-incubation of liver microsomes with methoxychlor and various P450 isoform-selective inhibitors suggested involvement of several P450s in mono-O-demethylation, including CYP1A2, CYP2A6, CYP2C9, and CYP2C19.
33(0,1,1,3) Details