Protein Information

Name CYP2C18
Synonyms CPCI; Flavoprotein linked monooxygenase; CYP2C; CYP2C17; CYP2C18; CYP2C18 protein; CYPIIC18; Cytochrome P450 2C18…

Compound Information

Name methoxychlor
CAS 1,1′-(2,2,2-trichloroethylidene)bis[4-methoxybenzene]

Reference List

PubMed Abstract RScore(About this table)
9733665 Stresser DM, Kupfer D: Human cytochrome P450-catalyzed conversion of the proestrogenic pesticide methoxychlor into an estrogen. Drug Metab Dispos. 1998 Sep;26(9):868-74.

Although CYP2C18 is an efficient methoxychlor demethylase, its expression in liver is reportedly low or absent, suggesting a negligible role for this enzyme in methoxychlor metabolism.
38(0,1,2,3) Details