Protein Information

Name ID1
Synonyms DNA binding protein inhibitor ID 1; ID; ID1; Inhibitor of DNA binding 1; Inhibitor of differentiation 1; Inhibitor of DNA binding 1s; Inhibitor of differentiation 1s

Compound Information

Name methoxychlor
CAS 1,1′-(2,2,2-trichloroethylidene)bis[4-methoxybenzene]

Reference List

PubMed Abstract RScore(About this table)
7574712 Zhou LX, Dehal SS, Kupfer D, Morrell S, McKenzie BA, Eccleston ED Jr, Holtzman JL: Cytochrome P450 catalyzed covalent binding of methoxychlor to rat hepatic, microsomal iodothyronine 5'-monodeiodinase, type I: does exposure to methoxychlor disrupt thyroid hormone metabolism?. Arch Biochem Biophys. 1995 Oct 1;322(2):390-4.

We now have found that during hepatic, microsomal metabolism of [ring-14C]- or [3H-OCH3] methoxychlor, their metabolite primarily binds to iodothyronine 5'-monodeiodinase, type I (5'-ID1).		 200(2,3,4,5) Details