Protein Information

Name protoporphyrinogen oxidase
Synonyms Mutant protoporphyrinogen oxidase; VP; PPO; PPOX; Protoporphyrinogen oxidase; V290M; Protoporphyrinogen oxidases

Compound Information

Name fomesafen
CAS

Reference List

PubMed Abstract RScore(About this table)
8653563 Krijt J, Maruna P, Petrovicky P, Janousek V: The effect of protoporphyrinogen oxidase inhibitors on microsomal and mitochondrial cytochromes. Obes Res. 1995 Dec;3 Suppl 5:785S-788S.

To test this possibility, the content of brain mitochondrial cytochrome a3 was determined after intracerebroventricular administration of the protoporphyrinogen oxidase-inhibiting herbicide fomesafen.
163(2,2,2,3) Details
8045477 Krijt J, Vokurka M, Sanitrak J, Janousek V, van Holsteijn I, Blaauboer BJ: Effect of the protoporphyrinogen oxidase-inhibiting herbicide fomesafen on liver uroporphyrin and heptacarboxylic porphyrin in two mouse strains. Food Chem Toxicol. 1994 Jul;32(7):641-50.
162(2,2,2,2) Details
12758057 Krijt J, Psenak O, Vokurka M, Chlumska A, Fakan F: Experimental hepatic uroporphyria induced by the diphenyl-ether herbicide fomesafen in male DBA/2 mice. Toxicol Appl Pharmacol. 2003 May 15;189(1):28-38.

However, feeding of the protoporphyrinogen oxidase-inhibiting herbicide fomesafen (0.25% in the diet for 18 weeks) induced hepatic uroporphyria in male DBA/2N mice (liver porphyrin content up to 150 nmol/g, control animals 1 nmol/g), whereas fomesafen-treated male C57BL/6N mice displayed only a slight elevation of liver porphyrins (approximately 5 nmol/g).
81(1,1,1,1) Details
12723887 Miller RP, Martinson KB, Sothern RB, Durgan BR, Gunsolus JL: Circadian response of annual weeds in a natural setting to high and low application rates of four herbicides with different modes of actions. Chronobiol Int. 2003 Mar;20(2):299-324.

Four herbicides [glyphosate (GLYT), an amino acid synthesis inhibitor; glufosinate (GLUF), a glutamine synthetase inhibitor; fomesafen (FOME), a protoporphyrinogen oxidase inhibitor, and chlorimuron ethyl (CLIM), an acetolactate synthase inhibitor] were used to examine the influence of time of day of application on the control of a variety of annual broadleaf weeds in field studies conducted in Minnesota (five studies on GLYT and GLUF, three studies on FOME and CLIM).
31(0,1,1,1) Details
15656167 Trezzi MM, Felippi CL, Mattei D, Silva HL, Nunes AL, Debastiani C, Vidal RA, Marques A: Multiple resistance of acetolactate synthase and protoporphyrinogen oxidase inhibitors in Euphorbia heterophylla biotypes. J Environ Sci Health B. 2005;40(1):101-9.

In the greenhouse experiment samples of each population were sprayed with imazethapyr or fomesafen, at only one rate.
1(0,0,0,1) Details