| Name | C18 |
|---|---|
| Synonyms | B1; D1; BBS 9; BBS9; BBS9 GENE; Bardet Biedl syndrome 9 protein; C18; PTH responsive osteosarcoma B1 protein… |
| Name | benzalkonium chloride |
|---|---|
| CAS | quaternary ammonium compounds, alkylbenzyldimethyl, chlorides |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 11504045 | So TS, Huie CW: Salting-out solvent extraction for the off-line preconcentration of benzalkonium chloride in capillary electrophoresis. Electrophoresis. 2001 Jul;22(11):2143-9. Using benzalkonium chloride (BAK) as model compound, a mixture of cationic surfactants consisting of even-numbered alkylbenzyl quaternary ammonium homologues (C8-C18), the addition of appropriate amounts of and acetonitrile in the sample solution (2 mL sample volume) was found to be capable of providing ca. 40-fold enhancement in detection sensitivity. |
6(0,0,1,1) | Details |
| 10985577 | Russell JA, Malcolm RK, Campbell K, Woolfson AD: High-performance liquid chromatographic determination of 17beta- and 17beta--3- solubilities and diffusion coefficents in silicone elastromeric intravaginal rings. J Chromatogr B Biomed Sci Appl. 2000 Jul 7;744(1):157-63. Both steroid peaks have been fully resolved from the benzalkonium chloride peaks by the reported chromatographic method, which employs a C18 bonded reversed-phase column, an acetonitrile-water (50:50, v/v) mobile phase and a UV detection wavelength of 281 nm. |
6(0,0,1,1) | Details |
| 3937663 | Iohan F, Jackanicz T, Monder C: Measurement of and levonorgestrel incorporated into sustained release contraceptive formulations. Contraception. 1985 Dec;32(6):571-80. High performance liquid chromatography was used to measure the concentrations of (EE) and levonorgestrel (LNG) released from contraceptive devices into aqueous medium containing the cationic detergent, benzalkonium chloride. Over the course of many injections into octasilyl (C8) or octadecylsilyl (C18) reversed-phase columns, the chromatographic profile of EE was gradually altered with multiple peaks emerging. |
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| 2612790 | Herman JR, Bass P: Enteric neuronal ablation: structure-activity relationship in a series of alkyldimethylbenzylammonium chlorides. Fundam Appl Toxicol. 1989 Oct;13(3):576-84. Serosal application of a commercial solution of benzalkonium chloride (BAC) has been shown to selectively ablate myenteric neurons in the rat jejunum. Seven ADBAC homologs with alkyl chain lengths ranging from C6 to C18 were tested. |
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| 12113992 | Song KH, An HM, Kim HJ, Ahn SH, Chung SJ, Shim CK: Simple liquid chromatography-electrospray ionization mass spectrometry method for the routine determination of salmon calcitonin in serum. J Chromatogr B Analyt Technol Biomed Life Sci. 2002 Aug 5;775(2):247-55. The residue was then reconstituted with 57% acetonitrile in water containing 0.1% trifluoroacetic acid and 0.005% benzalkonium chloride. A 20-microl aliquot of the reconstituted solution was injected onto a polymer based RP-C18 column, The outlet was connected to an ion-trap mass spectrometer equipped with an ESI source, and spectra were recorded in a positive-ion, selected-ion monitoring mode. |
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| 9659709 | Kawakami S, Callicott RH, Zhang N: Trace analysis of benzalkonium chloride on skin by flow injection ionspray mass spectrometry-mass spectrometry. Analyst. 1998 Mar;123(3):489-91. Quantification was carried out using an external standard based on peak area summation of each benzalkonium ion (C8, C10, C12, C14, C16 and C18) in the mass spectra. |
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| 16316068 | Rojsitthisak P, Wichitnithad W, Pipitharome O, Sanphanya K, Thanawattanawanich P: Simple HPLC determination of benzalkonium chloride in ophthalmic formulations containing antazoline and tetrahydrozoline. PDA J Pharm Sci Technol. 2005 Sep-Oct;59(5):332-7. The ophthalmic solution samples can be directly analyzed by reversed-phase on HiQ-Sil C18 column (4.6 mm x 150 mm, i.d., 5-microm particle size) with acetonitrile- buffer (pH 5.0; 0.2 M) (70:30, v/v) as mobile phase. |
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| 11105866 | Herrero-Martinez JM, Simo-Alfonso EF, Mongay-Fernandez C, Ramis-Ramos G: Determination of cationic surfactants by capillary zone electrophoresis and micellar electrokinetic chromatography with micelles in the presence of large organic solvent concentrations. J Chromatogr A. 2000 Oct 20;895(1-2):227-35. Mixtures of the cationic surfactants benzalkonium chloride (BKC) and cetylpyridinium (CPC) were quickly resolved and reproducibly and reliably determined by using background electrolytes (BGEs) containing 80 mM borate, pH 8.5, bile salts and large concentrations of an organic solvent. When the bile salt is present, the separation mechanism changes from capillary zone electrophoresis (CZE) to a mixed micellar electrokinetic chromatography (MEKC)-CZE, with predominant MEKC interactions, which lead to an excellent resolution of all the solutes, including the C12-C18 homologues of BKC and CPC. |
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| 15595655 | Nunez O, Moyano E, Galceran MT: Determination of quaternary ammonium biocides by liquid chromatography-mass spectrometry. J Chromatogr A. 2004 Nov 26;1058(1-2):89-95. In this study we have developed a method for the direct determination of benzalkonium chloride (BAC) homologues and didecyldimethylammonium (DDMAC), generally used as biocides. The chromatographic separation was performed using a Luna C18 column and gradient elution. |
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| 1474126 | Elrod L Jr, Golich TG, Morley JA: Determination of benzalkonium chloride in eye care products by high-performance liquid chromatography and solid-phase extraction or on-line column switching. J Chromatogr. 1992 Nov 20;625(2):362-7. The analytes are separated from various product excipients and concentrated by either solid-phase extraction onto Sep-Pak C18 cartridges or by an on-line column-switching technique using 1-cm reversed-phase precolumns. |
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| 11432568 | Ferrer I, Furlong ET: Identification of alkyl dimethylbenzylammonium surfactants in water samples by solid-phase extraction followed by ion trap LC/MS and LC/MS/MS. Environ Sci Technol. 2001 Jun 15;35(12):2583-8. A novel methodology was developed for the determination of alkyl (C12, C14, and C16) dimethylbenzylammonium (benzalkonium chloride or BAC, Chemical Abstract Service number: 8001-54-5) in water samples. Chromatographic separation was achieved for three BAC homologues by using a C18 column and a gradient of acetonitrile/10 millimolar aqueous ammonium |
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| 17011092 | Martinez-Carballo E, Gonzalez-Barreiro C, Sitka A, Kreuzinger N, Scharf S, Gans O: Determination of selected quaternary ammonium compounds by liquid chromatography with mass spectrometry. Environ Pollut. 2007 Mar;146(2):543-7. Epub 2006 Sep 28. In general sediments were especially contaminated by C12 chain benzalkonium chloride (BAC-C12) as well as by the long C-chain dialkyldimethylammonium (DDAC-C18) with a maximum concentration of 3.6 mg/kg and 2.1mg/kg, respectively. |
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| 18715840 | Swiercz R, Halatek T, Wasowicz W, Kur B, Grzelinska Z, Majcherek W: Pulmonary irritation after inhalation exposure to benzalkonium chloride in rats. Int J Occup Med Environ Health. 2008;21(2):157-63. BACKGROUND: Benzalkonium chloride (BAC) is a quaternary ammonium compound (QAC) with a C8 to C18 chain length of alkyl groups. |
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